ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2024
The Relationship Between Small Dense Low-Density Lipoprotein Cholesterol and Metabolic Syndrome.
Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 7 citations in OpenAlex.
- Small Dense Low-density Lipoprotein Cholesterol as a Prognostic Risk Factor in Premature Acute Coronary Syndrome with Multivessel Disease: A Retrospective Cohort Study.Journal of atherosclerosis and thrombosis · 2026Article
- Single point insulin sensitivity estimator index is associated with predominance of atherogenic small, dense low-density lipoprotein cholesterol particles in Korean obese adults: a retrospective study.Korean journal of family medicine · 2026Article
- Article
- Small dense LDL: An underestimated driver of atherosclerosis (Review).Molecular medicine reports · 2025Review
- Role of ChREBP-PPARα-FGF21 Axis in Metabolic Dysfunction of MASLD.International journal of molecular sciences · 2025Article
- Association between atherogenic index of plasma and sepsis in critically ill patients with ischemic stroke: a retrospective cohort study using propensity score and machine learning approaches.Lipids in health and disease · 2025Article
- Predicting Metabolic Syndrome Using Supervised Machine Learning: A Multivariate Parameter Approach.International journal of molecular sciences · 2025Article
- Association of estimated small dense low-density lipoprotein cholesterol with diabetes mellitus: a large-scale multicenter retrospective cohort study.BMC endocrine disorders · 2025Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Prior research has established an association between small dense low-density lipoprotein cholesterol (sdLDL-C) and dyslipidemia, serving as a significant marker for predicting cardiovascular diseases. Nevertheless, the connection between sdLDL-C and metabolic syndrome (MetS) remains unclear. Methods: This study retrospectively analyzed 23,187 individuals who underwent health checkups at Taizhou Hospital's health management center. Here, we investigated the relationship between sdLDL-C and MetS, along with its components, utilizing Spearman correlation analysis, receiver operating characteristic (ROC) curve analysis, logistic regression, and mediation analysis. Results: The MetS group exhibited significantly higher level of sdLDL-C compared to the non-MetS group ( Conclusion: The sdLDL-C is correlated with MetS and it can successfully mediate the relationship between GGT and TG. Our data suggests that sdLDL-c and GGT are suitable parameters for preventing and monitoring MetS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.