Evidence map›Paper›PMID 38576447›Full record

ArticleFrontiers in bioengineering and biotechnology2024

Site-selective fatty acid chain conjugation of the N-terminus of the recombinant human granulocyte colony-stimulating factor.

Xu-Dong Wang, Zhi-Hao Su, Jie Du, Wei-Jia Yu, Wen-Long Sun

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Xu-Dong WangCollege of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, China.
Zhi-Hao SuCollege of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, China.
Jie DuCollege of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, China.
Wei-Jia YuCollege of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, China.
Wen-Long SunInstitute of Biomedical Research, School of Life Sciences, Shandong University of Technology, Zibo, China.
Zhejiang University of Technology · CNShandong University of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The clinical application of the recombinant human granulocyte colony-stimulating factor (rhG-CSF) is restricted by its short serum half-life. Herein, site-selective modification of the N-terminus of rhG-CSF with PAL-PEG

Indexed as

fatty acid chain conjugationlong-acting rhG-CSFrecombinant human granulocyte colony-stimulating factorrhG-CSFserum half-lifesite-selective modification

Identifiers

PMID38576447
PMCPMC10993259
OpenAlexW4392923365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.