Evidence map›Paper›PMID 38576398›Full record

ArticleAmerican journal of hypertension2024

Trends in the Prevalence of Multiple Chronic Conditions Among US Adults With Hypertension From 1999-2000 Through 2017-2020.

Chibuike J Alanaeme, Lama Ghazi, Oluwasegun P Akinyelure, Ying Wen, Ashley Christenson, Bharat Poudel, Erin E Dooley, Ligong Chen, Shakia T Hardy, Kathryn Foti and 4 more

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in American journal of hypertension, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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  6. Uncovering the mechanistic basis ofPharmaceutical biology · 2025
    Article
  7. Article
  8. Article
  9. Cardiovascular Risk Prediction in Older Adults.Current atherosclerosis reports · 2025
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Chibuike J AlanaemeDepartment of Epidemiology, The University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0003-2792-1259
Lama GhaziDepartment of Epidemiology, The University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0002-9930-3575
Oluwasegun P AkinyelureDepartment of Epidemiology, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Ying WenDepartment of Epidemiology, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Ashley ChristensonDepartment of Epidemiology, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Bharat PoudelDepartment of Epidemiology, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Erin E DooleyDepartment of Epidemiology, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Ligong ChenDepartment of Epidemiology, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Shakia T HardyDepartment of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Kathryn FotiDepartment of Epidemiology, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
C Barrett BowlingDepartment of Medicine, Duke University, Durham, North Carolina, USA.
Michelle T LongSection of Gastroenterology, Department of Medicine, Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.
Lisandro D ColantonioDepartment of Epidemiology, The University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0001-8742-1788
Paul MuntnerDepartment of Epidemiology, The University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0002-4711-5492
University of Alabama at Birmingham · USDuke University · USUniversity of North Carolina at Chapel Hill · US

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Institutional Career Development CoreKL2TR001874 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GENKINGER, JEANINE M., SHIMBO, DAICHI · 2016 to 2025
$13.6M
Evaluating novel approaches for estimating awake and sleep blood pressureR01HL139716 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEVITAN, EMILY B, SHIMBO, DAICHI · 2018 to 2021
$3.4M
Peer Support for Lowering Blood Pressure among Adolescents: A Pilot, Randomized Controlled TrialK01HL164763 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Shakia Tranece Hardy · 2022 to 2026
$729k
NCATS NIH HHS KL2 TR001874NCATS NIH HHS UL1 TR001873NHLBI NIH HHS K01 HL164763NHLBI NIH HHS R01 HL139716
6 · The paper itself

Abstract

backgroundThe prevalence of many chronic conditions has increased among US adults. Many adults with hypertension have other chronic conditions.

methodsWe estimated changes in the age-adjusted prevalence of multiple (≥3) chronic conditions, not including hypertension, using data from the National Health and Nutrition Examination Survey, from 1999-2000 to 2017-2020, among US adults with (n = 24,851) and without (n = 24,337 hypertension. Hypertension included systolic blood pressure (BP) ≥130 mm Hg, diastolic BP ≥80 mm Hg, or antihypertensive medication use. We studied 14 chronic conditions: arthritis, asthma, cancer, coronary heart disease, chronic kidney disease, depression, diabetes, dyslipidemia, hepatitis B, hepatitis C, heart failure, lung disease, obesity, and stroke.

resultsFrom 1999-2000 to 2017-2020, the age-adjusted mean number of chronic conditions increased more among US adults with vs. without hypertension (2.2 to 2.8 vs. 1.7 to 2.0; P-interaction <0.001). Also, the age-adjusted prevalence of multiple chronic conditions increased from 39.0% to 52.0% among US adults with hypertension and from 26.0% to 30.0% among US adults without hypertension (P-interaction = 0.022). In 2017-2020, after age, gender, and race/ethnicity adjustment, US adults with hypertension were 1.94 (95% confidence interval: 1.72-2.18) times as likely to have multiple chronic conditions compared to those without hypertension. In 2017-2020, dyslipidemia, obesity, and arthritis were the most common 3 co-occurring chronic conditions among US adults with and without hypertension (age-adjusted prevalence 16.5% and 3.1%, respectively).

conclusionsIn 2017-2020, more than half of US adults with hypertension had ≥3 additional chronic conditions, a substantial increase from 20 years ago.

Indexed as

HypertensionMultiple Chronic ConditionsNutrition SurveysAdultAgedBlood PressureFemaleHumansMaleMiddle AgedMultimorbidityPrevalenceRisk FactorsTime FactorsUnited StatesYoung Adultblood pressurechronic conditionsepidemiologyhypertensionmultimorbidityNHANES

Identifiers

PMID38576398
PMCPMC11519032
OpenAlexW4394019124

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.