Evidence map›Paper›PMID 38576234›Full record

ArticleThe Korean journal of internal medicine2024

Self-screening questionnaire for perianal fistulizing disease in patients with Crohn's disease.

O Seong Kweon, Ben Kang, Yoo Jin Lee, Eun Soo Kim, Sung Kook Kim, Hyun Seok Lee, Yun Jin Chung, Kyeong Ok Kim, Byung Ik Jang, Crohn’s Colitis Association in Daegu-Gyeongbuk (CCAiD)

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The Korean journal of internal medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

O Seong KweonDivision of Gastroenterology, Department of Internal Medicine, Kyungpook National University, School of Medicine, Daegu, Korea.
Ben KangDepartment of Pediatrics, Kyungpook National University, School of Medicine, Daegu, Korea.
Yoo Jin LeeDivision of Gastroenterology, Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea.
Eun Soo KimDivision of Gastroenterology, Department of Internal Medicine, Kyungpook National University, School of Medicine, Daegu, Korea.
Sung Kook KimDivision of Gastroenterology, Department of Internal Medicine, Kyungpook National University, School of Medicine, Daegu, Korea.
Hyun Seok LeeDivision of Gastroenterology, Department of Internal Medicine, Kyungpook National University, School of Medicine, Daegu, Korea.
Yun Jin ChungDivision of Gastroenterology, Department of Internal Medicine, Kyungpook National University, School of Medicine, Daegu, Korea.
Kyeong Ok KimDivision of Gastroenterology, Department of Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea.
Byung Ik JangDivision of Gastroenterology, Department of Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea.
Crohn’s Colitis Association in Daegu-Gyeongbuk (CCAiD)
Kyungpook National University · KRKeimyung University · KRYeungnam University College

Funding

Kyungpook National University Hospital
6 · The paper itself

Abstract

BACKGROUND/

aimsA poor prognostic factor for Crohn's disease (CD) includes perianal fistulizing disease, including perianal fistula and/or perianal abscess. Currently, a tool to assess perianal symptoms in patients with CD remains nonexistent. This study aimed to develop a perianal fistulizing disease self-screening questionnaire for patients with CD.

methodsThis prospective pilot study was conducted at three tertiary referral centers between January 2019 and May 2020. We formulated questions on perianal symptoms, including tenesmus, anal discharge, bleeding, pain, and heat. A 4-point Likert scale was used to rate each question. Patients with CD completed a questionnaire and underwent pelvic magnetic resonance imaging (MRI).

resultsOverall, 93 patients were enrolled, with 51 (54.8%) diagnosed with perianal fistulizing disease, as determined by pelvic MRI. The Spearman correlation findings demonstrated that anal pain (p = 0.450, p < 0.001) and anal discharge (p = 0.556, p < 0.001) were the symptoms that most significantly correlated with perianal disease. For anal pain and discharge, the area under the receiver operating characteristic curve of the scores was significantly higher than that of the combined score for all five symptoms (0.855 vs. 0.794, DeLong's test p = 0.04). For the two symptoms combined, the sensitivity, specificity, and positive predictive and negative predictive values were 88.2, 73.8, 80.4, and 83.8%, respectively, with 81.7% accuracy for detecting perianal fistulizing disease.

conclusionThis study indicates that simple questions regarding anal pain and discharge can help accurately identify the presence of perianal fistulizing disease in patients with CD.

Indexed as

Crohn DiseaseMagnetic Resonance ImagingPredictive Value of TestsRectal FistulaAdultFemaleHumansMaleMiddle AgedPilot ProjectsProspective StudiesReproducibility of ResultsSurveys and QuestionnairesYoung AdultPerianal diseasePerianal fistulizing Crohn’s diseaseScreening tool

Identifiers

PMID38576234
PMCPMC11076884
OpenAlexW4393988328

What OpenQuestion holds

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LicenceCC BY-NC
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.