Evidence map›Paper›PMID 38576136›Full record

ReviewMass spectrometry reviews

Protein glycosylation in lung cancer from a mass spectrometry perspective.

Mirjam Balbisi, Simon Sugár, Lilla Turiák

Open access · hybridAbstract readReview
In one paragraph

Review in Mass spectrometry reviews. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 8 citations in OpenAlex.

  1. Glycan Fingerprint of Malignant Pleural Mesothelioma.International journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Mirjam BalbisiMTA-TTK Lendület (Momentum) Glycan Biomarker Research Group, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary.ORCID 0000-0002-6917-6974
Simon SugárMTA-TTK Lendület (Momentum) Glycan Biomarker Research Group, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary.
Lilla TuriákMTA-TTK Lendület (Momentum) Glycan Biomarker Research Group, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary.ORCID 0000-0002-2139-8156
Centre for Social Sciences · HUSemmelweis University · HU

Funding

János Bolyai Research Scholarship of the Hungarian Academy of SciencesLendület (Momentum) Program of the Hungarian Academy of Sciences (HAS, MTA)National Research, Development, and Innovation Fund of Hungary 2018-1.2.1-NKP-2018-00005National Research, Development, and Innovation Fund of Hungary FK 131603National Research, Development, and Innovation Fund of Hungary FK_19 FUNDING SCHEME
6 · The paper itself

Abstract

Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer. Differences in glycosylation patterns have been previously observed between healthy and cancerous samples as well as between different lung cancer subtypes, which suggests untapped diagnostic potential. In addition, understanding the changes mediated by glycosylation may shed light on possible novel therapeutic targets and personalized treatment strategies for lung cancer patients. Mass spectrometry based glycomics and glycoproteomics have emerged as powerful tools for in-depth characterization of changes in protein glycosylation, providing valuable insights into the molecular basis of lung cancer. This paper reviews the literature on the analysis of protein glycosylation in lung cancer using mass spectrometry, which is dominated by manuscripts published over the past 5 years. Studies analyzing N-glycosylation, O-glycosylation, and glycosaminoglycan patterns in tissue, serum, plasma, and rare biological samples of lung cancer patients are highlighted. The current knowledge on the potential utility of glycan and glycoprotein biomarkers is also discussed.

Indexed as

GlycoproteinsLung NeoplasmsMass SpectrometryAnimalsBiomarkers, TumorGlycomicsGlycosaminoglycansGlycosylationHumansPolysaccharidesProteomicsBiomarkers, TumorGlycoproteinsGlycosaminoglycansPolysaccharidesglycosaminoglycanlung cancermass spectrometryN‐glycosylationO‐glycosylation

Identifiers

PMID38576136
PMCPMC13062607
OpenAlexW4393984122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.