ArticleMagnetic resonance in medicine2024
MR signature matching (MRSIGMA) implementation for true real-time free-breathing volumetric imaging with sub-200 ms latency on an MR-Linac.
Article in Magnetic resonance in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 4 citations in OpenAlex.
- 3D and 4D Free-Breathing Abdominal T1-Weighted MRI in Clinical Practice Using Deep Learning Auto-Navigation and Reconstruction.Magnetic resonance in medicine · 2026Article
- Dynamic Mode Decomposition (DMD) for Low-Latency Real-Time Cardiac MRI.Magnetic resonance in medicine · 2026Article
- High-definition motion-resolved MRI using 3D radial kooshball acquisition and deep learning spatial-temporal 4D reconstruction.Physics in medicine and biology · 2025Article
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Authors and funding
8 authors at 2 institutions in 2 countries.
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Abstract
purposeDevelop a true real-time implementation of MR signature matching (MRSIGMA) for free-breathing 3D MRI with sub-200 ms latency on the Elekta Unity 1.5T MR-Linac.
methodsMRSIGMA was implemented on an external computer with a network connection to the MR-Linac. Stack-of-stars with partial k
resultsMotion dictionary was computed in under 5 s. Signature acquisition and matching presented 173 ms latency on the phantom and 193 ms on patients. MRSIGMA presented a mean error of 1.3-1.6 mm for all phantom experiments, which was below the 2 mm acquisition resolution along the motion direction. The Dice coefficient over time between MRSIGMA and reference contours was 0.88 ± 0.02 (GTV), 0.87 ± 0.02(duodenum-stomach), and 0.78 ± 0.02(small bowel), demonstrating high motion tracking performance for both tumor and organs at risk.
conclusionThe real-time implementation of MRSIGMA enabled true real-time free-breathing 3D MRI with sub-200 ms imaging latency on a clinical MR-Linac system, which can be used for treatment monitoring, adaptive radiotherapy and dose accumulation mapping in tumors affected by respiratory motion.
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