Evidence map›Paper›PMID 38576115›Full record

ArticleMovement disorders clinical practice2024

Molecular Imaging in CANVAS: A Contribution for Differential Diagnosis?

Tatiana Horowitz, Eric Guedj, Alexandre Eusebio, Frédérique Fluchère, Jean-Philippe Azulay, Emilien Delmont, Stephan Grimaldi

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Movement disorders clinical practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Tatiana HorowitzNuclear Medicine Department, Aix Marseille Univ, APHM, CNRS, Centrale Marseille, Institut Fresnel, Timone Hospital, CERIMED, Marseille, France.ORCID https://orcid.org/0000-0003-1977-309X
Eric GuedjNuclear Medicine Department, Aix Marseille Univ, APHM, CNRS, Centrale Marseille, Institut Fresnel, Timone Hospital, CERIMED, Marseille, France.
Alexandre EusebioNeurology and Movement Disorders Department, APHM, Timone University Hospital, Marseille, France.
Frédérique FluchèreNeurology and Movement Disorders Department, APHM, Timone University Hospital, Marseille, France.
Jean-Philippe AzulayNeurology and Movement Disorders Department, APHM, Timone University Hospital, Marseille, France.
Emilien DelmontNeurology Department, Reference Center for Neuromuscular Diseases and ALS, Public Assistance Hospitals of Marseille, Timone University Hospital, Marseille, France.
Stephan GrimaldiNeurology and Movement Disorders Department, APHM, Timone University Hospital, Marseille, France.
Assistance Publique Hôpitaux de Marseille · FRCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPhenotypes of CANVAS are increasingly diversified, including bradykinesia and dysautonomia, so that its primary differential diagnoses are multiple system atrophy-cerebellar type (MSA-c), and spinocerebellar ataxia type 3 (SCA3). This case series aims to highlight key molecular imaging findings in CANVAS. CASES: We report a case series of six patients with CANVAS who underwent nuclear medicine examinations in our center and 13 patients from the literature. These include

conclusionsIn CANVAS,

Indexed as

Tomography, Emission-Computed, Single-Photon3-IodobenzylguanidineAgedBrainDiagnosis, DifferentialDopamine Plasma Membrane Transport ProteinsFemaleFluorodeoxyglucose F18HumansMachado-Joseph DiseaseMaleMiddle AgedMolecular ImagingMultiple System AtrophyPositron-Emission Tomography3-IodobenzylguanidineDopamine Plasma Membrane Transport ProteinsFluorodeoxyglucose F18CANVAScerebellar ataxia with neuropathy and bilateral vestibular Areflexia syndromeDATSCANPETSPECT

Identifiers

PMID38576115
PMCPMC11233850
OpenAlexW4393987036

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.