Evidence map›Paper›PMID 38575967›Full record

ArticleInternational journal of health geographics2024

Comparison of geographical and individual deprivation index to assess the risk of Sars-CoV-2 infection and disease severity: a retrospective cohort study.

Sara Mazzilli, Gianluca Paparatto, Antonio Chieti, Anna Maria Nannavecchia, Lucia Bisceglia, Pier Luigi Lopalco, Domenico Martinelli, Lara Tavoschi

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Article in International journal of health geographics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Sara MazzilliScuola Normale Superiore, Pisa, Italy. sara.mazzilli@sns.it.
Gianluca PaparattoDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Antonio ChietiStrategic Regional Health and Social Agency of Puglia (AReSS Puglia), Bari, Italy.
Anna Maria NannavecchiaStrategic Regional Health and Social Agency of Puglia (AReSS Puglia), Bari, Italy.
Lucia BiscegliaStrategic Regional Health and Social Agency of Puglia (AReSS Puglia), Bari, Italy.
Pier Luigi LopalcoDepartment of Biological and Environmental Sciences and Technology, University of Salento, Lecce, Italy.
Domenico MartinelliHygiene Unit, Policlinico Foggia Hospital, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
Lara TavoschiDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt has been shown that COVID-19 affects people at socioeconomic disadvantage more strongly. Previous studies investigating the association between geographical deprivation and COVID-19 outcomes in Italy reported no differences in case-hospitalisation and case-fatality. The objective of this research was to compare the usefulness of the geographic and individual deprivation index (DI) in assessing the associations between individuals' deprivation and risk of Sars-CoV-2 infection and disease severity in the Apulia region from February to December 2020.

methodsThis was a retrospective cohort study. Participants included individuals tested for SARS-CoV-2 infection during the study period. The individual DI was calculated employing polychoric principal component analysis on four census variables. Multilevel logistic models were used to test associations between COVID-19 outcomes and individual DI, geographical DI, and their interaction.

resultsIn the study period, 139,807 individuals were tested for COVID-19 and 56,475 (43.5%) tested positive. Among those positive, 7902 (14.0%) have been hospitalised and 2215 (4.2%) died. During the first epidemic wave, according the analysis done with the individual DI, there was a significant inversely proportional trend between the DI and the risk of testing positive. No associations were found between COVID-19 outcomes and geographic DI. During the second wave, associations were found between COVID-19 outcomes and individual DI. No associations were found between the geographic DI and the risk of hospitalisation and death. During both waves, there were no association between COVID-19 outcomes and the interaction between individual and geographical DI.

conclusionsEvidence from this study shows that COVID-19 pandemic has been experienced unequally with a greater burden among the most disadvantaged communities. The results of this study remind us to be cautious about using geographical DI as a proxy of individual social disadvantage because may lead to inaccurate assessments. The geographical DI is often used due to a lack of individual data. However, on the determinants of health and health inequalities, monitoring has to have a central focus. Health inequalities monitoring provides evidence on who is being left behind and informs equity-oriented policies, programmes and practices. Future research and data collection should focus on improving surveillance systems by integrating individual measures of inequalities into national health information systems.

Indexed as

COVID-19HumansPandemicsPatient AcuityRetrospective StudiesSARS-CoV-2ApuliaCOVID-19Deprivation indexItalySars-CoV-2Socioeconomic disadvantage

Identifiers

PMID38575967
PMCPMC10993505

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.