ArticleBMC cardiovascular disorders2024
Investigating the interplay of smoking, cardiovascular risk factors, and overall cardiovascular disease risk: NHANES analysis 2011-2018.
Article in BMC cardiovascular disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Association between early menopause and adverse cardiovascular events in postmenopausal women: a systematic review and meta-analysis stratified by smoking status and type 2 diabetes mellitus.Frontiers in public health · 2026Pooled it
- Tobacco Smoking and Cardiovascular Health in Africa: Trends, Interventions, and Policy Implications-A Narrative Review.Health science reports · 2026Article
- Cardiovascular Diseases: Exploring Epidemiology, Pathophysiology, Risk Factors, and Medicinal Plant-Based Therapies: A Narrative Review.Health science reports · 2026Article
- Dose‑dependent association of smoking exposure with HDL subfraction cholesterol content.Scientific reports · 2026Article
- Directions and Perspectives for Preventive Activities in Primary Care-Patients' Health-Promoting and Health-Risk Behaviours.Nutrients · 2026Observational
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- Cardiovascular disease risk and associated factors among people with hypertension in the West Bank, Palestine.Frontiers in cardiovascular medicine · 2026Article
- Frailty transitions and risk of chronic kidney disease: insights from the China Health and Retirement Longitudinal Study.Renal failure · 2025Article
- Nicotine consumption and folate insufficiency in pregnancy: a population-based cross-sectional study.The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2025Article
- GLP-1 Receptor Agonist Indications and Prescriptions Among Adults Who Do and Do Not Smoke.Diabetes care · 2025Article
- Review
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- Comparison of mortality trends in patients with rheumatic mitral valve disease and nonrheumatic mitral valve disease: A retrospective study in US from 1999 to 2020.International journal of cardiology. Heart & vasculature · 2025Article
- Secondhand smoke is associated with abdominal obesity and high obesity index in a large Taiwanese population study.Scientific reports · 2025Article
- Increased Left Ventricular Myocardial Extracellular Volume Assessed by Cardiac Computed Tomography as a Consequence of Aortic Stenosis and Coexisting Cardiovascular Risk Factors.Journal of clinical medicine · 2025Article
- Risk Factors Associated With the Occurrence and Recurrence of Benign Paroxysmal Positional Vertigo in Koreans: A Nested Case-Control Study.Clinical and experimental otorhinolaryngology · 2025Article
- Biomarker-based risk assessment of dietary intervention in patients with coronary artery disease during cardiac rehabilitation-a quasi-experimental study.Frontiers in nutrition · 2025Article
- Smoking-Associated Changes in Gene Expression in Coronary Artery Disease Patients Using Matched Samples.Current issues in molecular biology · 2024Article
- Trend of Metabolic Syndrome Indicators in Working Korean Women According to Smoking Status and Workplace Size: A Population-Based Retrospective Longitudinal Study.Public health nursing (Boston, Mass.)Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study explores the intricate relationship between smoking, cardiovascular disease (CVD) risk factors and their combined impact on overall CVD risk, utilizing data from NHANES 2011-2018.
methodsParticipants were categorized based on the presence of CVD, and we compared their demographic, social, and clinical characteristics. We utilized logistic regression models, receiver operating characteristics (ROC) analysis, and the chi-squared test to examine the associations between variables and CVD risk.
resultsSignificant differences in characteristics were observed between those with and without CVD. Serum cotinine levels exhibited a dose-dependent association with CVD risk. The highest quartile of cotinine levels corresponded to a 2.33-fold increase in risk. Smoking, especially in conjunction with lower HDL-c, significantly increases CVD risk. Combinations of smoking with hypertension, central obesity, diabetes, and elevated triglycerides also contributed to increased CVD risk. Waist-to-Height Ratio, Visceral Adiposity Index, A Body Shape Index, Conicity Index, Triglyceride-Glucose Index, Neutrophil, Mean platelet volume and Neutrophil to Lymphocyte ratio demonstrated significant associations with CVD risk, with varying levels of significance post-adjustment. When assessing the combined effect of smoking with multiple risk factors, a combination of smoking, central obesity, higher triglycerides, lower HDL-c, and hypertension presented the highest CVD risk, with an adjusted odds ratio of 14.18.
conclusionSmoking, when combined with central obesity, higher triglycerides, lower HDL-c, and hypertension, presented the highest CVD risk, with an adjusted odds ratio of 14.18.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.