Evidence map›Paper›PMID 38575876›Full record

ArticleBMC genomics2024

DhuFAP: a platform for gene functional analysis in Dendrobium huoshanense.

Qiaoqiao Xiao, Qi Pan, Jun Li, Jinqiang Zhang, Jiaotong Yang

Abstract read
In one paragraph

Article in BMC genomics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Qiaoqiao XiaoResource Institute for Chinese and Ethnic Materia Medica, Guizhou University of Traditional Chinese Medicine, 550025, Guizhou, China.
Qi PanResource Institute for Chinese and Ethnic Materia Medica, Guizhou University of Traditional Chinese Medicine, 550025, Guizhou, China.
Jun LiResource Institute for Chinese and Ethnic Materia Medica, Guizhou University of Traditional Chinese Medicine, 550025, Guizhou, China.
Jinqiang ZhangResource Institute for Chinese and Ethnic Materia Medica, Guizhou University of Traditional Chinese Medicine, 550025, Guizhou, China. 552450374@qq.com.
Jiaotong YangResource Institute for Chinese and Ethnic Materia Medica, Guizhou University of Traditional Chinese Medicine, 550025, Guizhou, China. y_jiaotong@163.com.

Funding

National Natural Science Foundation of China NO.32260140Research Project of Guizhou Dendrobium Industry Development Center Qian ShikēHé [2019006]the Guizhou Provincial Science and Technology Projects ZK[2022]505the National and Provincial Scientific and Technological Innovation Talent Team of the Guizhou University of Traditional Chinese Medicine GZYTDHZ[2022]003the University Science and Technology Innovation Team of the Guizhou Provincial Department of Education ([2023]071
6 · The paper itself

Abstract

backgroundDendrobium huoshanense, a traditional medicinal and food plant, has a rich history of use. Recently, its genome was decoded, offering valuable insights into gene function. However, there is no comprehensive gene functional analysis platform for D. huoshanense.

resultTo address this, we created a platform for gene function analysis and comparison in D. huoshanense (DhuFAP). Using 69 RNA-seq samples, we constructed a gene co-expression network and annotated D. huoshanense genes by aligning sequences with public protein databases. Our platform contained tools like Blast, gene set enrichment analysis, heatmap analysis, sequence extraction, and JBrowse. Analysis revealed co-expression of transcription factors (C2H2, GRAS, NAC) with genes encoding key enzymes in alkaloid biosynthesis. We also showcased the reliability and applicability of our platform using Chalcone synthases (CHS).

conclusionDhuFAP ( www.gzybioinformatics.cn/DhuFAP ) and its suite of tools represent an accessible and invaluable resource for researchers, enabling the exploration of functional information pertaining to D. huoshanense genes. This platform stands poised to facilitate significant biological discoveries in this domain.

Indexed as

DendrobiumReproducibility of ResultsDendrobium huoshanenseGene function analysisGene Set enrichment analysisPlatform

Identifiers

PMID38575876
PMCPMC10996181

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