Evidence map›Paper›PMID 38575380›Full record

Trial reportPrilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki)2024

Evaluation of the Effects of Gastro Protect as an Alternative Medicine on Gastritis and Other Gastrointestinal Symptoms.

Dafina Nikolova, Meri Trajkovska, Emilija Nikolovska Trpcevska, Vladimir Andreevski, Kalina Grivceva Stardelova, Vesna Velic

Open access · diamondAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Dafina NikolovaUniversity clinic of Gastroenterohepatology, Faculty of Medicine, University "Ss Cyril and Methodius", Skopje, RN Macedonia.
Meri TrajkovskaUniversity clinic of Gastroenterohepatology, Faculty of Medicine, University "Ss Cyril and Methodius", Skopje, RN Macedonia.
Emilija Nikolovska TrpcevskaUniversity clinic of Gastroenterohepatology, Faculty of Medicine, University "Ss Cyril and Methodius", Skopje, RN Macedonia.
Vladimir AndreevskiUniversity clinic of Gastroenterohepatology, Faculty of Medicine, University "Ss Cyril and Methodius", Skopje, RN Macedonia.
Kalina Grivceva StardelovaUniversity clinic of Gastroenterohepatology, Faculty of Medicine, University "Ss Cyril and Methodius", Skopje, RN Macedonia.
Vesna VelicDepartment of Epidemiology and Biostatistics, Faculty of Medicine, University "Ss Cyril and Methodius", Skopje, RN Macedonia.
Saints Cyril and Methodius University of Skopje · MK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe use of herbal medicine as a part of the Complementary and Alternative Medicine is increasing worldwide. Herbal remedies are used to better different conditions including gastritis. MATERIAL AND

methodsWe conducted a prospective randomized control clinical trial on a total sample of 72 patients with gastritis in order to examine the effects of the commercial herbal product Gastro Protect. After 6 weeks of conventional therapy the patients were divided into two groups with 36 patients each. As a continuation of the treatment, Group 1 received conventional therapy + Gastro Protect and Group 2 received conventional therapy + Placebo. We analyzed 14 selected gastrointestinal symptoms, five related to digestive problems, and nine related to stool and bowel problems. For assessing the selected symptoms we used seven point gastrointestinal symptom rating scale (GSRS).

resultsThe Gastro Protect group had a significantly lower GSRS score (better condition) compared to the Placebo group related to all five selected symptoms of digestive problems as: abdominal pain (p=0.0250), hunger pain (p=0.0276), nausea (p=0.0019), heartburn (p=0.00001), and acid reflux (p=0.0017). The Gastro Protect group, also had a significantly lower GSRS score (better condition) compared to the Placebo group related to three out of nine selected bowel symptoms: rumbling (p=0.0022), abdominal distension (p=0.0029), and gas or flatus (p=0.0039).

conclusionGastro protect was effective in treating gastritis and other gastrointestinal symptoms. It was safe for usage and showed almost no side effects. In our study, Gastro Protect reduced the examined gastric symptoms and related examined intestinal symptoms.

Indexed as

Complementary TherapiesGastritisGastroesophageal RefluxHumansProspective StudiesQuality of Lifealternative medicinegastritisgastrointestinal symptomsherbal medicine

Identifiers

PMID38575380
OpenAlexW4393930292

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.