Evidence map›Paper›PMID 38575341›Full record

ArticleRenal failure2024

Myofibroblast-derived exosomes enhance macrophages to myofibroblasts transition and kidney fibrosis.

Wenqiang Yu, Jinfang Song, Shuangquan Chen, Jiayi Nie, Chujun Zhou, Jiamin Huang, Hua Liang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Renal failure, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Macrophage-Fibroblast Crosstalk in Kidney Injury: A Narrative Review.International journal of molecular sciences · 2026
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  9. Effect of macrophage-to-myofibroblast transition on silicosis.Animal models and experimental medicine · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Wenqiang YuDepartment of Anesthesiology, Foshan Women and Children Hospital, Foshan, China.
Jinfang SongZhuhai Campus, Zunyi Medical University, Zhuhai, China.
Shuangquan ChenDepartment of Anesthesiology, Foshan Women and Children Hospital, Foshan, China.
Jiayi NieDepartment of Anesthesiology, Foshan Women and Children Hospital, Foshan, China.
Chujun ZhouJiangxi University of Traditional Chinese Medicine, Nanchang, China.
Jiamin HuangDepartment of Anesthesiology, Foshan Women and Children Hospital, Foshan, China.
Hua LiangDepartment of Anesthesiology, Foshan Women and Children Hospital, Foshan, China.
Foshan Maternity and Child Health Care Hospital · CNJiangxi University of Traditional Chinese Medicine · CNZunyi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A critical event in the pathogenesis of kidney fibrosis is the transition of macrophages into myofibroblasts (MMT). Exosomes play an important role in crosstalk among cells in the kidney and the development of renal fibrosis. However, the role of myofibroblast-derived exosomes in the process of MMT and renal fibrosis progression remains unknown. Here, we examined the role of myofibroblast-derived exosomes in MMT and kidney fibrogenesis.

Indexed as

ExosomesKidney DiseasesAnimalsFibrosisKidneyMacrophagesMiceMyofibroblastsExosomesmacrophagesmyofibroblastsrenal fibrosis

Identifiers

PMID38575341
PMCPMC10997357
OpenAlexW4394739975

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.