Evidence map›Paper›PMID 38575154›Full record

ArticleBMJ open diabetes research & care2024

Influence of diabetes and other risk factors on in-hospital mortality following kidney transplantation: an analysis of the Spanish National Hospital Discharge Database from 2016 to 2020.

Ana Lopez-de-Andres, Rodrigo Jimenez-Garcia, Marta Lopez-Herranz, José Javier Zamorano-Leon, David Carabantes-Alarcon, Valentin Hernandez-Barrera, Javier de Miguel-Diez, Francisco Carricondo, Barbara Romero-Gomez, Natividad Cuadrado-Corrales

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Article in BMJ open diabetes research & care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Ana Lopez-de-AndresDepartment of Public Health & Maternal and Child Health, Faculty of Medicine, Universidad Complutense de Madrid, Madrid, Spain.
Rodrigo Jimenez-GarciaDepartment of Public Health & Maternal and Child Health, Universidad Complutense de Madrid, Madrid, Spain rodrijim@ucm.es.ORCID 0000-0001-5906-9393
Marta Lopez-HerranzNursing Department, Faculty of Nursing, Physiotherapy and Podology, Universidad Complutense de Madrid, Madrid, Spain.
José Javier Zamorano-LeonDepartment of Public Health & Maternal and Child Health, Universidad Complutense de Madrid, Madrid, Spain.
David Carabantes-AlarconDepartment of Public Health & Maternal and Child Health, Universidad Complutense de Madrid, Madrid, Spain.
Valentin Hernandez-BarreraPreventive Medicine and Public Health Teaching and Research Unit, Health Sciences Faculty, Universidad Rey Juan Carlos, Mostoles, Spain.
Javier de Miguel-DiezRespiratory Care Department, Hospital General Universitario Gregorio Maranon, Madrid, Spain.
Francisco CarricondoDepartment of Immunology, Laboratory of Neurobiology of Hearing (UCM 910915), Ophthalmology and Otorhinolaryngology, Faculty of Medicine, Universidad Complutense de Madrid, Madrid, Spain.
Barbara Romero-GomezDepartment of Immunology, Laboratory of Neurobiology of Hearing (UCM 910915), Ophthalmology and Otorhinolaryngology, Faculty of Medicine, Universidad Complutense de Madrid, Madrid, Spain.
Natividad Cuadrado-CorralesDepartment of Public Health & Maternal and Child Health, Universidad Complutense de Madrid, Madrid, Spain.
Universidad Complutense de Madrid · ESHospital General Universitario Gregorio Marañón · ESUniversidad Rey Juan Carlos · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTo assess time trends in incidence, clinical characteristics, complications, and hospital outcomes among patients with type 1 diabetes (T1D), with type 2 diabetes (T2D), and patients without diabetes who underwent kidney transplant (KT); to identify variables associated with in-hospital mortality (IHM); and to determine the impact of the COVID-19 pandemic. RESEARCH DESIGN AND

methodsWe used a nationwide discharge database to select KT recipients admitted to Spanish hospitals from 2016 to 2020. We stratified patients according to diabetes status. We used multivariable logistic regression to identify the variables associated with IHM.

resultsA total of 14 594 KTs were performed in Spain (T2D, 22.28%; T1D, 3.72%). The number of KTs rose between 2016 and 2019 and and decreased from 2019 to 2020 in all groups. In patients with T2D, the frequency of KT complications increased from 21.08% in 2016 to 34.17% in 2020 (p<0.001). Patients with T2D had significantly more comorbidity than patients with T1D and patients without diabetes (p<0.001). Patients with T1D experienced KT rejection significantly more frequently (8.09%) than patients with T2D (5.57%).COVID-19 was recorded in 26 out of the 2444 KTs performed in 2020, being found in 6 of the 39 patients deceased that year (15.38%) and in 0.83% of the survivors.The variables associated with IHM were comorbidity and complications of KT. The presence of T1D was associated with IHM (OR 2.6; 95% CI 1.36 to 5.16) when patients without diabetes were the reference category. However, T2D was not associated with a higher IHM (OR 0.86; 95% CI 0.61 to 1.2).

conclusionsThe COVID-19 pandemic led to a decrease in the number of transplants. Patients with T1D have more rejection of the transplanted organ than patients with T2D. Fewer women with T2D undergo KT. The presence of T1D is a risk factor for IHM.

Indexed as

COVID-19Diabetes Mellitus, Type 1Diabetes Mellitus, Type 2Kidney TransplantationFemaleHospital MortalityHospitalsHumansPandemicsPatient DischargeRisk FactorsCOVID-19IncidenceKidney TransplantationType 2 Diabetes

Identifiers

PMID38575154
PMCPMC11002393
OpenAlexW4393953331

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