Evidence map›Paper›PMID 38574278›Full record

ArticleAIDS care2024

Barriers and facilitators to pre-exposure prophylaxis (PrEP) uptake and adherence among men who have sex with men (MSM) in Thailand: a qualitative study.

Yeon Jung Yu, Elizabeth Schieber, Rena Janamnuaysook, Bo Wang, Abhinaya Gunasekar, Karen MacDonell, Pintusorn Getwongsa, Deogwoon Kim, Prissana Wongharn, Nittaya Phanuphak

Registry-linked trialAbstract read
In one paragraph

Article in AIDS care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05243030 (Adapting Effective mHealth Interventions to Improve Uptake and Adherence of the HIV Pre-exposure Prophylaxis), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05243030 nacompletednot on this map

Adapting Effective mHealth Interventions to Improve Uptake and Adherence of the HIV Pre-exposure Prophylaxis (PrEP) in Thai Young Men Who Have Sex With Men (MSM).

TypeinterventionalSponsorUniversity of Massachusetts, WorcesterRan2022 to 2025Enrolled119ConditionsPre-Exposure ProphylaxisArmsMotivational Enhancement System for PrEP Uptake and Adherence (MES-PrEP), Motivational Interactive Text Messaging (MTM), Standard PrEP Counseling
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. International journal of molecular sciences · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yeon Jung YuDepartment of Anthropology, Western Washington University, Bellingham, WA, USA.
Elizabeth SchieberDepartment of Population and Quantitative Health Sciences, The University of Massachusetts Chan Medical School, Worcester, MA, USA.
Rena JanamnuaysookInstitute of HIV Research and Innovation (IHRI), Bangkok, Thailand.
Bo WangDepartment of Population and Quantitative Health Sciences, The University of Massachusetts Chan Medical School, Worcester, MA, USA.
Abhinaya GunasekarDepartment of Population and Quantitative Health Sciences, The University of Massachusetts Chan Medical School, Worcester, MA, USA.
Karen MacDonellDepartment of Behavioral Sciences and Social Medicine, Florida State University College of Medicine, Tallahassee, FL, USA.
Pintusorn GetwongsaInstitute of HIV Research and Innovation (IHRI), Bangkok, Thailand.
Deogwoon KimDepartment of Population and Quantitative Health Sciences, The University of Massachusetts Chan Medical School, Worcester, MA, USA.
Prissana WongharnCenter of Excellence for Pediatric Infectious Diseases and Vaccines, Chulalongkorn University, Bangkok, Thailand.
Nittaya PhanuphakInstitute of HIV Research and Innovation (IHRI), Bangkok, Thailand.

Funding

Adapting effective mhealth interventions to improve uptake and adherence of the HIV pre- exposure prophylaxis (PrEP) in Thai young MSMR34MH124081 · NIMH · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI PHANUPHAK, NITTAYA, WANG, BO · 2021 to 2023
$671k
Optimizing an mHealth intervention to improve uptake and adherence of the HIV pre-exposure prophylaxis (PrEP) in vulnerable adolescents and emerging adultsR21HD107988 · NICHD · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI MACDONELL, KAREN, PHANUPHAK, NITTAYA · 2021 to 2022
$404k
NICHD NIH HHS R21 HD107988NIMH NIH HHS R34 MH124081
6 · The paper itself

Abstract

Young MSM (YMSM), aged 15-24, account for nearly half of new HIV infections in Thailand. Pre-exposure prophylaxis (PrEP) is an effective prevention medicine for populations at substantial HIV risk, yet YMSM frequently have suboptimal uptake of and adherence to PrEP. We conducted 35 in-depth interviews with YMSM to explore barriers and facilitators of both PrEP initiation and adherence. Interviews also elicited the perceptions and experiences of healthcare providers (HCPs) working with YMSM at three clinics in Bangkok. Primary barriers to PrEP initiation were limited accessibility, insufficient knowledge, and efficacy concerns; HCPs identified no-to-low self-perception of HIV risk, pre-existing health problems, fears of side effects, and living in distant provinces as barriers to PrEP initiation. YMSM primarily reported PrEP information and self-perceptions of elevated HIV risk as facilitators to PrEP initiation. Additionally, forgetfulness and low HIV risk awareness were common barriers to PrEP adherence. Reminders were a prominent facilitator of PrEP adherence alongside disclosure to close relationships, the routinization of regimens, and convenient facilities. HCPs regarded counseling as the leading facilitator of PrEP adherence. By understanding the barriers/facilitators of PrEP use, the current study seeks to help develop evidence-informed PrEP intervention programs among YMSM while considering cultural sensitivity.

Indexed as

Anti-HIV AgentsHealth Knowledge, Attitudes, PracticeHIV InfectionsHomosexuality, MaleMedication AdherencePre-Exposure ProphylaxisQualitative ResearchAdolescentAdultHealth PersonnelHumansInterviews as TopicMalePatient Acceptance of Health CareThailandYoung AdultAnti-HIV AgentsHIVmen who have sex with men (MSM)pre-exposure prophylaxis (PrEP)SDG 3: Good health and well-beingSDG 5: Gender equalityThailand

Identifiers

PMID38574278
PMCPMC12637369

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.