Evidence map›Paper›PMID 38574144›Full record

ArticleScience (New York, N.Y.)2024

Prophage terminase with tRNase activity sensitizes

Siva Uppalapati, Sashi Kant, Lin Liu, Ju-Sim Kim, David Orlicky, Michael McClelland, Andres Vazquez-Torres

Open access · greenAbstract read
In one paragraph

Article in Science (New York, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Revisiting the life cycle of temperate phages.Nature reviews. Microbiology · 2026
    Review
  2. Article
  3. An Integrated DNA Nanoprobe for Intranuclear Imaging and In Situ Profiling of OGG1 Activity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Dual role of phage terminase inEngineering microbiology · 2024
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Siva Uppalapati *University of Colorado School of Medicine, Department of Immunology and Microbiology, Aurora, CO, USA.ORCID 0000-0002-4743-7248
Sashi Kant *University of Colorado School of Medicine, Department of Immunology and Microbiology, Aurora, CO, USA.ORCID 0000-0002-9015-8383
Lin LiuUniversity of Colorado School of Medicine, Department of Immunology and Microbiology, Aurora, CO, USA.
Ju-Sim KimUniversity of Colorado School of Medicine, Department of Immunology and Microbiology, Aurora, CO, USA.ORCID 0000-0002-4932-4490
David OrlickyUniversity of Colorado School of Medicine, Department of Pathology, Aurora, CO, USA.ORCID 0000-0002-0417-1400
Michael McClellandDepartment of Microbiology and Molecular Genetics, University of California Irvine School of Medicine, Irvine, CA, USA.ORCID 0000-0003-1788-9347
Andres Vazquez-TorresUniversity of Colorado School of Medicine, Department of Immunology and Microbiology, Aurora, CO, USA.ORCID 0000-0002-6181-4185
University of Colorado Denver · USUniversity of California, Irvine · USVA Eastern Colorado Health Care System · US

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Melanie Funes · 1994 to 2026
$57.9M
Salmonella evasion of NADPH oxidase-dependent killingR01AI054959 · NIAID · UNIVERSITY OF COLORADO DENVER · PI VAZQUEZ-TORRES, ANDRES · 2003 to 2018
$5.2M
Molecular determinants of oxidative stress in Salmonella pathogenesisR01AI136520 · NIAID · UNIVERSITY OF COLORADO DENVER · PI Andres Vazquez-Torres · 2018 to 2026
$3.7M
Barcoding a Salmonella gene knockout libraryR03AI139557 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI MCCLELLAND, MICHAEL · 2019 to 2020
$157k
Molecular Analysis of Bacterial Adaptive Response to Host Reactive SpeciesI01BX002073 · VA · VA EASTERN COLORADO HEALTH CARE SYSTEM · PI Andres Vazquez-Torres · 2013 to 2026
–
BLRD Research Career Scientist Award ApplicationIK6BX005384 · VA · VA EASTERN COLORADO HEALTH CARE SYSTEM · PI VAZQUEZ-TORRES, ANDRES · 2021 to 2025
–
BLRD VA I01 BX002073BLRD VA IK6 BX005384NCI NIH HHS P30 CA062203NIAID NIH HHS R01 AI054959NIAID NIH HHS R01 AI136520NIAID NIH HHS R03 AI139557
6 · The paper itself

Abstract

Phage viruses shape the evolution and virulence of their bacterial hosts. The

Indexed as

EndodeoxyribonucleasesProphagesSalmonella entericaSalmonella PhagesViral ProteinsAnimalsOxidative StressRNARNA, TransferEndodeoxyribonucleasesGipA protein, Phage Gifsy-1RNARNA, TransferterminaseViral Proteins

Identifiers

PMID38574144
PMCPMC11443816
OpenAlexW4393928592

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.