Evidence map›Paper›PMID 38574091›Full record

ArticlePloS one2024

Comparison of lumbar muscle morphology in patients with chronic nonspecific low back pain with and without clinical lumbar segmental instability.

Faranak Mahmoudi Alami, Mohammad Taghipour, Ghadamali Talebi, Payam Sa'adat, Tahere Seyedhoseinpoor, Hamid Vahidi Rad, Sorayya Khafri

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Paraspinal muscle quality in chronic low back pain: a systematic review and meta-analysis of muscle atrophy and fat infiltration.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Pooled it
  2. Trial
  3. Spinal mobility and paraspinal muscle degeneration: a cross-sectional analysis from the Berlin Back Study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  4. Review
  5. Article
  6. The influence of sarcopenia on clinical and radiological features in patients with single-segment degenerative lumbar spondylolisthesis at L4/5 level.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  7. Fatty infiltration in the multifidus predicts screw-loosening following short-segment decompression and fusion: proof of why we should protect and rehabilitate the paraspinal muscles.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Faranak Mahmoudi AlamiFaculty of Rehabilitation Medicine, Department of Physiotherapy, Babol University of Medical Sciences, Babol, Iran.
Mohammad TaghipourHealth Research Institute, Mobility Impairment Research Center, Babol University of Medical Sciences, Babol, Iran.ORCID 0000-0002-6941-6595
Ghadamali TalebiHealth Research Institute, Mobility Impairment Research Center, Babol University of Medical Sciences, Babol, Iran.
Payam Sa'adatHealth Research Institute, Mobility Impairment Research Center, Babol University of Medical Sciences, Babol, Iran.
Tahere SeyedhoseinpoorHealth Research Institute, Mobility Impairment Research Center, Babol University of Medical Sciences, Babol, Iran.
Hamid Vahidi RadFaculty of Medicine, Department of Radiology, Mazandaran University of Medical Sciences, Sari, Iran.
Sorayya KhafriFaculty of Health, Department of Biostatistics and Epidemiology, Babol University of Medical Sciences, Babol, Iran.
Babol University of Medical Sciences · IRMazandaran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesEvaluation of spinal muscle morphology may be critical because of its impact on segmental stability and control of the lumbar spine in the subset of patients with clinical lumbar segmental instability (LSI). The purpose of this study was to compare lumbar muscle morphology in CNLBP patients with clinical LSI, CNLBP patients without clinical LSI.

methodsThis case-control study included 30 patients with CNLBP (15 with clinical LSI and 15 without clinical LSI) and 15 subjects without LBP. Axial magnetic resonance images from the L2 to S1 lumbar levels were used to evaluate the morphology of the lumbar muscles.

resultsA significant increase in the muscle-to-fat infiltration index and a significant decrease in the relative muscle cross-sectional area (rmCSA) of the multifidus muscle at the L3-L4 to L5-S1 levels were observed in both CNLBP groups compared to the control group (p<0.05). The mean erector spinae mean rmCSA was significantly greater in the clinical LSI group compared to the control group (SMD = 0.853, 95% CI = 0.105 to -1.6, P = 0.044) and also compared to the CNLBP without clinical LSI (SMD = 0.894, 95% CI = -1.645 to -0.144, P = 0.030) at the L4-L5 level.

conclusionsThe atrophic changes of the multifidus muscle, in CNLBP patients with or without clinical LSI was observed. However, hypertrophic changes of the erector spinae muscle at the L4-L5 lumbar level were observed only in the clinical LSI group. Psaos major did not show significant atrophic or hypertrophic changes.

Indexed as

Joint InstabilityLow Back PainSpinal DiseasesCase-Control StudiesHumansLumbar VertebraeMagnetic Resonance ImagingMuscular AtrophyParaspinal Muscles

Identifiers

PMID38574091
PMCPMC10994386
OpenAlexW4393929248

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.