Evidence map›Paper›PMID 38573556›Full record

ArticleEJNMMI research2024

Neuroimaging-guided diagnosis of possible FTLD-FUS pathology: a case report.

Gregory Mathoux, Cecilia Boccalini, Aurelien Lathuliere, Max Scheffler, Giovanni B Frisoni, Valentina Garibotto

Open access · goldAbstract read
In one paragraph

Article in EJNMMI research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Gregory MathouxDivision of Nuclear Medicine and Molecular Imaging, Geneva University Hospitals, Geneva, Switzerland.
Cecilia BoccaliniLaboratory of Neuroimaging and Innovative Molecular Tracers (NIMTlab), Faculty of Medicine, Geneva University Neurocenter, University of Geneva, Geneva, Switzerland.
Aurelien LathuliereDepartment of Rehabilitation and Geriatrics, Memory Clinic, Geneva University and University Hospitals, Geneva, Switzerland.
Max SchefflerDivision of Radiology, Geneva University Hospitals, Geneva, Switzerland.
Giovanni B FrisoniDepartment of Rehabilitation and Geriatrics, Memory Clinic, Geneva University and University Hospitals, Geneva, Switzerland.
Valentina GaribottoDivision of Nuclear Medicine and Molecular Imaging, Geneva University Hospitals, Geneva, Switzerland. Valentina.Garibotto@hcuge.ch.ORCID http://orcid.org/0000-0003-2422-698X
University of Geneva · CHUniversity Hospital of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis case report presents a patient with progressive memory loss and choreiform movements. CASE PRESENTATION: Neuropsychological tests indicated multi-domain amnestic mild cognitive impairment (aMCI), and neurological examination revealed asymmetrical involuntary hyperkinetic movements. Imaging studies showed severe left-sided atrophy and hypometabolism in the left frontal and temporoparietal cortex. [

conclusionsOur case highlights that despite the lack of specific FUS biomarkers the combination of clinical features and neuroimaging biomarkers can guide choosing the most likely differential diagnosis in a complex neurological case. Imaging in particular allowed an accurate measure of the topography and severity of neurodegeneration and the exclusion of AD-related pathology.

Indexed as

ChoreaFTLD-FUS pathologyMild cognitive impairmentNeuroimagingPET

Identifiers

PMID38573556
PMCPMC10994884
OpenAlexW4393938533

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.