Evidence map›Paper›PMID 38573550›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2024

Unilateral deep brain stimulation (DBS) of nucleus ventralis intermedius thalami (Vim) for the treatment of post-traumatic tremor in children: a multicentre experience.

Simone Peraio, Giorgio Mantovani, Tommaso Araceli, Lorenzo Mongardi, Alice Noris, Edoardo Fino, Francesca Formica, Luigi Piccinini, Federico Melani, Matteo Lenge and 8 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 3 countries.

Simone Peraio *Department of Neurosurgery, Meyer Children's Hospital IRCCS, Florence, Italy.
Giorgio Mantovani *Department of Translational Medicine and for Romagna, University of Ferrara, Ferrara, Italy.
Tommaso Araceli *Department of Neurosurgery, Meyer Children's Hospital IRCCS, Florence, Italy.
Lorenzo MongardiDepartment of Translational Medicine and for Romagna, University of Ferrara, Ferrara, Italy.
Alice NorisDepartment of Neurosurgery, Meyer Children's Hospital IRCCS, Florence, Italy.
Edoardo FinoPediatric Neurology Clinic - Meyer Children's Hospital IRCCS, Florence, Italy.
Francesca FormicaIstituto Medea "La Nostra Famiglia" IRCCS, Bosisio Parini, LC, Italy.
Luigi PiccininiIstituto Medea "La Nostra Famiglia" IRCCS, Bosisio Parini, LC, Italy.
Federico MelaniPediatric Neurology Clinic - Meyer Children's Hospital IRCCS, Florence, Italy.
Matteo LengePediatric Neurology Clinic - Meyer Children's Hospital IRCCS, Florence, Italy. matteo.lenge@meyer.it.
Roberta ScaliseIstituto Stella Maris - IRCCS - University of Pisa, Pisa, Italy.
Roberta BattiniIstituto Stella Maris - IRCCS - University of Pisa, Pisa, Italy.
Andrea Di RitaDepartment of Neurosurgery, Meyer Children's Hospital IRCCS, Florence, Italy.
Ludovico D'IncertiDepartment of Radiology, Meyer Children's Hospital IRCCS, Florence, Italy.
Tayler AppletonDepartment of Biology, Harding University, Searcy, AR, USA.
Michele Alessandro CavalloDepartment of Translational Medicine and for Romagna, University of Ferrara, Ferrara, Italy.
Renzo GuerriniPediatric Neurology Clinic - Meyer Children's Hospital IRCCS, Florence, Italy.
Flavio GiordanoDepartment of Neurosurgery, Meyer Children's Hospital IRCCS, Florence, Italy.
Meyer Children's Hospital · ITUniversity of Ferrara · ITFondazione Stella Maris · ITIRCCS Eugenio Medea · ITHarding University Main Campus · USIstituti di Ricovero e Cura a Carattere Scientifico · ITUniversity Hospital Regensburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDeep brain stimulation (DBS) of nucleus ventralis intermedius thalami (Vim) is a validated technique for the treatment of essential tremor (ET) in adults. Conversely, its use for post traumatic tremor (PTT) and in paediatric patients is still debated. We evaluated the efficacy of Vim-DBS for lesional tremor in three paediatric patients with drug-resistant post-traumatic unilateral tremor.

methodsWe retrospectively collected data regarding three patients with unilateral tremor due to severe head injury, with no MRI evidence of basal ganglia lesions. The three patients underwent stereotactic frame-based robot-assisted DBS of Vim contralateral to the tremor side.

resultsMean follow-up was 48 months (range: 36-60 months). Tremor was reduced in all patients with a better control of voluntary movements and improvement of functional status (mean FIM scale improvement + 7 points). No surgical complications occurred.

conclusionUnilateral contralateral DBS of Vim could be efficacious in post-traumatic tremor, even in paediatric patients and should be offered in PTT drug-resistant patients.

Indexed as

Deep Brain StimulationTremorVentral Thalamic NucleiAdolescentChildFemaleHumansMaleRetrospective StudiesTreatment OutcomeDeep brain stimulationNucleus ventralis intermedius thalamiPaediatricPost traumatic tremor

Identifiers

PMID38573550
OpenAlexW4393950521

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.