Evidence map›Paper›PMID 38573487›Full record

SynthesisSpine deformity2024

Implant density in adolescent idiopathic scoliosis: a meta-analysis of clinical and radiological outcomes.

Marven Aoun, Mohammad Daher, Aren-Joe Bizdikian, Gaby Kreichati, Khalil Kharrat, Amer Sebaaly

Abstract readMeta-AnalysisReview
PubMed Publisher
In one paragraph

Synthesis in Spine deformity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Posterior spinal fusion with pedicle screw-based constructs in osteogenesis imperfecta: a systematic review of surgical and radiographic outcomes.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Pooled it
  2. Pooled it
  3. Correction of adolescent idiopathic scoliosis using the convex rod de-rotation maneuver: a systematic review.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
    Pooled it
  4. Trial
  5. Review
  6. Review
  7. Article
  8. Evaluation of screw density in Lenke type 1 adolescent idiopathic scoliosis: are low and high-density constructs truly comparable?European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
    Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Marven AounSchool of Medicine, Saint Joseph University, Faculty of Medicine, Beirut, Lebanon.
Mohammad DaherSchool of Medicine, Saint Joseph University, Faculty of Medicine, Beirut, Lebanon.ORCID 0000-0002-9256-9952
Aren-Joe BizdikianDepartment of Orthopedic Surgery, Hotel Dieu de France Hospital, Alfred Naccache Boulevard, Beirut, Lebanon.
Gaby KreichatiSchool of Medicine, Saint Joseph University, Faculty of Medicine, Beirut, Lebanon.
Khalil KharratDepartment of Orthopedic Surgery, Hotel Dieu de France Hospital, Alfred Naccache Boulevard, Beirut, Lebanon.
Amer SebaalySchool of Medicine, Saint Joseph University, Faculty of Medicine, Beirut, Lebanon. amersebaaly@hotmail.com.
Saint Joseph University · LBHôtel-Dieu de France · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdolescent idiopathic scoliosis (AIS) affects 1-3% of adolescents, and treatment approaches, including the density of constructs in surgical fusion, vary among orthopedic surgeons. Studies have sought to establish whether high-density or low-density constructs offer superior clinical and radiological outcomes, yet conclusive results are lacking. This meta-analysis aims to provide a definitive answer to the controversial and ambiguous question surrounding the efficacy of different pedicle screw densities in treating AIS.

methodsPubMed, Cochrane, and Google Scholar (page 1-20) were searched till December 2023. The studied outcomes were Major Cobb angle, major curve correction, lumbar curve, kyphosis (T5-T12), lumbar lordosis, coronal balance, LIV Tilt angle, TAV translation, LAV translation, apical trunk rotation, trunk shift, SRS-22, operative time, blood loss, complications and cost.

resultsTwenty-four studies (total of 1985 patients, 1045 in LD group and 940 in HD group) were included in this meta-analysis. A statistically significant better improvement in ATR (p = 0.02) and LIV tilt angle (p = 0.02) was seen in the high-density group. On the other hand, longer operative time (p = 0.002), blood loss (p = 0.0004) and costs (p = 0.02) were seen in the high-density group. No difference was seen in the remaining radiographic and clinical outcomes between both surgeries.

conclusionBoth low-density (LD) and high-density (HD) screw constructs show comparable and satisfactory radiographic and QOL for AIS patients. Furthermore, HD constructs had increased costs, operative time, and blood loss associated. However, a definitive conclusion cannot be made and more studies taking into account multiple additional variables are necessary to do so.

Indexed as

Pedicle ScrewsScoliosisSpinal FusionAdolescentHumansLumbar VertebraeOperative TimeRadiographyTreatment OutcomeAdolescent idiopathic scoliosisImplant densityPedicle screws

Identifiers

PMID38573487
OpenAlexW4393949984

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.