Evidence map›Paper›PMID 38573173›Full record

ArticleAmerican journal of respiratory and critical care medicine2024

Pulmonary Ionocytes Regulate Airway Surface Liquid pH in Primary Human Bronchial Epithelial Cells.

Xiaojie Luan, Nicolas Henao Romero, Veronica A Campanucci, Yen Le, Jannatul Mustofa, Julian S Tam, Juan P Ianowski

Open access · hybridAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
9.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Potassium Channels of the Airway Epithelium.Acta physiologica (Oxford, England) · 2026
    Review
  3. Review
  4. Considerations for early life genetic therapies in cystic fibrosis.American journal of physiology. Lung cellular and molecular physiology · 2026
    Review
  5. Article
  6. Ascl3The Journal of physiology · 2026
    Article
  7. Article
  8. The Challenges of Detecting Neutrophil CFTR.Journal of innate immunity · 2026
    Review
  9. Article
  10. Review
  11. Pulmonary Ionocytes at the Crossroads of Absorption and Secretion: Clues from the Ferret.American journal of respiratory and critical care medicine · 2025
    Article
  12. Ionocyte CFTR Coordinates Chloride Absorption and Secretion to Balance Airway Fluid.American journal of respiratory and critical care medicine · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Do pulmonary ionocytes absorb chloride or secrete chloride?American journal of physiology. Cell physiology · 2025
    Review
  20. Lung stem cells and respiratory epithelial chimerism in transplantation.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Xiaojie LuanDepartment of Anatomy, Physiology, and Pharmacology.
Nicolas Henao RomeroDepartment of Anatomy, Physiology, and Pharmacology.
Veronica A CampanucciDepartment of Anatomy, Physiology, and Pharmacology.
Yen LeDepartment of Anatomy, Physiology, and Pharmacology.
Jannatul MustofaDepartment of Anatomy, Physiology, and Pharmacology.
Julian S TamRespiratory Research Centre, and.
Juan P IanowskiDepartment of Anatomy, Physiology, and Pharmacology.ORCID 0000-0003-4650-8531
Respiratory Clinical Trials · AUUniversity of Saskatchewan · CA

Funding

Cystic Fibrosis Canada 1034245Cystic Fibrosis Canada 555681Cystic Fibrosis Foundation 002367G221Institute of Circulatory and Respiratory Health 463882Institute of Circulatory and Respiratory Health 470114
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BronchiCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorEpithelial CellsAminophenolsCells, CulturedChloridesCyclic AMPHumansHydrogen-Ion ConcentrationIon TransportRespiratory MucosaSodiumAminophenolsCFTR protein, humanChloridesCyclic AMPCystic Fibrosis Transmembrane Conductance RegulatorSodiumclub cellscystic fibrosiselexacaftorionocytesivacaftortezacaftor

Identifiers

PMID38573173
PMCPMC11418883
OpenAlexW4393950056

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.