Evidence map›Paper›PMID 38573128›Full record

Trial reportRadiology. Cardiothoracic imaging2024

Performance of Image-navigated and Diaphragm-navigated 3D Late Gadolinium-enhanced Cardiac MRI for the Assessment of Atrial Fibrosis.

Luuk H G A Hopman, José A Solís-Lemus, Mark B M Hofman, Pranav Bhagirath, Sonia Borodzicz-Jazdzyk, Nikki van Pouderoijen, Axel J Krafft, Michaela Schmidt, Cornelis P Allaart, Steven A Niederer and 1 more

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Radiology. Cardiothoracic imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Radiology. Cardiothoracic imaging · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 4 countries.

Luuk H G A HopmanFrom the Department of Cardiology, Amsterdam UMC, De Boelelaan 1118, 1081 HV, Amsterdam, the Netherlands (L.H.G.A.H., P.B., S.B.J., N.v.P., C.P.A., M.J.W.G.); Division of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom (J.A.S.L., S.A.N.); Department of Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam, the Netherlands (M.B.M.H.); 1st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland (S.B.J.); and Siemens Healthineers, Erlangen, Germany (A.J.K., M.S.).ORCID 0000-0002-3896-9920
José A Solís-LemusFrom the Department of Cardiology, Amsterdam UMC, De Boelelaan 1118, 1081 HV, Amsterdam, the Netherlands (L.H.G.A.H., P.B., S.B.J., N.v.P., C.P.A., M.J.W.G.); Division of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom (J.A.S.L., S.A.N.); Department of Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam, the Netherlands (M.B.M.H.); 1st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland (S.B.J.); and Siemens Healthineers, Erlangen, Germany (A.J.K., M.S.).ORCID 0000-0002-2596-7811
Mark B M HofmanFrom the Department of Cardiology, Amsterdam UMC, De Boelelaan 1118, 1081 HV, Amsterdam, the Netherlands (L.H.G.A.H., P.B., S.B.J., N.v.P., C.P.A., M.J.W.G.); Division of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom (J.A.S.L., S.A.N.); Department of Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam, the Netherlands (M.B.M.H.); 1st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland (S.B.J.); and Siemens Healthineers, Erlangen, Germany (A.J.K., M.S.).ORCID 0000-0001-6532-8216
Pranav BhagirathFrom the Department of Cardiology, Amsterdam UMC, De Boelelaan 1118, 1081 HV, Amsterdam, the Netherlands (L.H.G.A.H., P.B., S.B.J., N.v.P., C.P.A., M.J.W.G.); Division of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom (J.A.S.L., S.A.N.); Department of Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam, the Netherlands (M.B.M.H.); 1st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland (S.B.J.); and Siemens Healthineers, Erlangen, Germany (A.J.K., M.S.).ORCID 0000-0003-3732-9304
Sonia Borodzicz-JazdzykFrom the Department of Cardiology, Amsterdam UMC, De Boelelaan 1118, 1081 HV, Amsterdam, the Netherlands (L.H.G.A.H., P.B., S.B.J., N.v.P., C.P.A., M.J.W.G.); Division of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom (J.A.S.L., S.A.N.); Department of Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam, the Netherlands (M.B.M.H.); 1st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland (S.B.J.); and Siemens Healthineers, Erlangen, Germany (A.J.K., M.S.).
Nikki van PouderoijenFrom the Department of Cardiology, Amsterdam UMC, De Boelelaan 1118, 1081 HV, Amsterdam, the Netherlands (L.H.G.A.H., P.B., S.B.J., N.v.P., C.P.A., M.J.W.G.); Division of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom (J.A.S.L., S.A.N.); Department of Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam, the Netherlands (M.B.M.H.); 1st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland (S.B.J.); and Siemens Healthineers, Erlangen, Germany (A.J.K., M.S.).
Axel J KrafftFrom the Department of Cardiology, Amsterdam UMC, De Boelelaan 1118, 1081 HV, Amsterdam, the Netherlands (L.H.G.A.H., P.B., S.B.J., N.v.P., C.P.A., M.J.W.G.); Division of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom (J.A.S.L., S.A.N.); Department of Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam, the Netherlands (M.B.M.H.); 1st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland (S.B.J.); and Siemens Healthineers, Erlangen, Germany (A.J.K., M.S.).
Michaela SchmidtFrom the Department of Cardiology, Amsterdam UMC, De Boelelaan 1118, 1081 HV, Amsterdam, the Netherlands (L.H.G.A.H., P.B., S.B.J., N.v.P., C.P.A., M.J.W.G.); Division of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom (J.A.S.L., S.A.N.); Department of Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam, the Netherlands (M.B.M.H.); 1st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland (S.B.J.); and Siemens Healthineers, Erlangen, Germany (A.J.K., M.S.).ORCID 0000-0003-1074-4209
Cornelis P AllaartFrom the Department of Cardiology, Amsterdam UMC, De Boelelaan 1118, 1081 HV, Amsterdam, the Netherlands (L.H.G.A.H., P.B., S.B.J., N.v.P., C.P.A., M.J.W.G.); Division of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom (J.A.S.L., S.A.N.); Department of Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam, the Netherlands (M.B.M.H.); 1st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland (S.B.J.); and Siemens Healthineers, Erlangen, Germany (A.J.K., M.S.).ORCID 0000-0002-0506-9512
Steven A NiedererFrom the Department of Cardiology, Amsterdam UMC, De Boelelaan 1118, 1081 HV, Amsterdam, the Netherlands (L.H.G.A.H., P.B., S.B.J., N.v.P., C.P.A., M.J.W.G.); Division of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom (J.A.S.L., S.A.N.); Department of Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam, the Netherlands (M.B.M.H.); 1st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland (S.B.J.); and Siemens Healthineers, Erlangen, Germany (A.J.K., M.S.).
Marco J W GötteFrom the Department of Cardiology, Amsterdam UMC, De Boelelaan 1118, 1081 HV, Amsterdam, the Netherlands (L.H.G.A.H., P.B., S.B.J., N.v.P., C.P.A., M.J.W.G.); Division of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom (J.A.S.L., S.A.N.); Department of Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam, the Netherlands (M.B.M.H.); 1st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland (S.B.J.); and Siemens Healthineers, Erlangen, Germany (A.J.K., M.S.).ORCID 0000-0001-9713-3675
GGD Amsterdam · NLKing's College London · GBMedical University of Warsaw · PL

Funding

Using Atrial Mechanics To Identify Fibrosis In Patients with Atrial FibrillationR01HL152256 · NHLBI · STANFORD UNIVERSITY · PI ENNIS, DANIEL B · 2020 to 2023
$2.8M
British Heart Foundation PG/13/37/30280British Heart Foundation PG/15/91/31812NHLBI NIH HHS R01 HL152256Wellcome TrustWellcome Trust WT 203148/Z/16/Z
6 · The paper itself

Abstract

Purpose To perform a qualitative and quantitative evaluation of the novel image-navigated (iNAV) 3D late gadolinium enhancement (LGE) cardiac MRI imaging strategy in comparison with the conventional diaphragm-navigated (dNAV) 3D LGE cardiac MRI strategy for the assessment of left atrial fibrosis in atrial fibrillation (AF). Materials and Methods In this prospective study conducted between April and September 2022, 26 consecutive participants with AF (mean age, 61 ± 11 years; 19 male) underwent both iNAV and dNAV 3D LGE cardiac MRI, with equivalent spatial resolution and timing in the cardiac cycle. Participants were randomized in the acquisition order of iNAV and dNAV. Both, iNAV-LGE and dNAV-LGE images were analyzed qualitatively using a 5-point Likert scale and quantitatively (percentage of atrial fibrosis using image intensity ratio threshold 1.2), including testing for overlap in atrial fibrosis areas by calculating Dice score. Results Acquisition time of iNAV was significantly lower compared with dNAV (4.9 ± 1.1 minutes versus 12 ± 4 minutes,

Indexed as

Atrial FibrillationDiaphragmAgedContrast MediaFemaleGadoliniumHeart AtriaHumansMagnetic Resonance ImagingMaleMiddle AgedProspective StudiesContrast MediaGadolinium

Identifiers

PMID38573128
PMCPMC11056763
OpenAlexW4393933148

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.