Evidence map›Paper›PMID 38573124›Full record

ArticleJournal of the American Chemical Society2024

Dual-Capped Helical Interface Mimics.

Tianxiong Mi, Zhe Gao, Zeynep Mituta, Kevin Burgess

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Forces behind N- and C-capping of peptidic helices.Chemical communications (Cambridge, England) · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tianxiong MiDepartment of Chemistry, Texas A & M University, Box 30012, College Station, Texas 77842, United States.
Zhe GaoDepartment of Chemistry, Texas A & M University, Box 30012, College Station, Texas 77842, United States.
Zeynep MitutaZentriForce Pharma Research GmbH, Carl-Friedrich-Gauss-Ring 5, 69124 Heidelberg, Germany.
Kevin BurgessDepartment of Chemistry, Texas A & M University, Box 30012, College Station, Texas 77842, United States.ORCID 0000-0001-6597-1842

Funding

Mid-sized GDNF Minics for Neural regenerationR21NS130471 · NINDS · TEXAS A&M UNIVERSITY · PI BURGESS, KEVIN · 2023 to 2024
$537k
NINDS NIH HHS R21 NS130471
6 · The paper itself

Abstract

Disruption of protein-protein interactions is medicinally important. Interface helices may be mimicked in helical probes featuring enhanced rigidities, binding to protein targets, stabilities in serum, and cell uptake. This form of mimicry is dominated by stapling between side chains of helical residues: there has been less progress on helical

Indexed as

PeptidesProtein Structure, SecondaryProteolysisPeptides

Identifiers

PMID38573124
PMCPMC11027154

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.