Evidence map›Paper›PMID 38572798›Full record

ArticleEuropean stroke journal2024

Characteristics and outcomes of cerebral venous thrombosis associated with COVID-19.

Adrian Scutelnic, Anita van de Munckhof, Angel T Miraclin, Sanjith Aaron, Sajid Hameed, Mohammad Wasay, Oxana Grosu, Katarzyna Krzywicka, Mayte Sánchez van Kammen, Erik Lindgren and 36 more

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in European stroke journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Cerebral venous thrombosis: Current management, recent advances and future directions.International journal of stroke : official journal of the International Stroke Society · 2025
    Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

46 authors at 20 institutions in 18 countries.

Adrian ScutelnicDepartment of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID 0000-0001-9053-584X
Anita van de MunckhofDepartment of Neurology, Amsterdam UMC, location University of Amsterdam, Amsterdam, The Netherlands.
Angel T MiraclinDepartment of Neurosciences, Christian Medical College Hospital, Vellore, Tamil Nadu, India.
Sanjith AaronDepartment of Neurosciences, Christian Medical College Hospital, Vellore, Tamil Nadu, India.
Sajid HameedAga Khan University, Karachi, Pakistan.
Mohammad WasayAga Khan University, Karachi, Pakistan.
Oxana GrosuInstitute of Neurology and Neurosurgery "Diomid Gherman," Chisinau, Republic of Moldova.
Katarzyna KrzywickaDepartment of Neurology, Amsterdam UMC, location University of Amsterdam, Amsterdam, The Netherlands.
Mayte Sánchez van KammenDepartment of Neurology, Amsterdam UMC, location University of Amsterdam, Amsterdam, The Netherlands.
Erik LindgrenDepartment of Neurology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Tiago MoreiraDepartment of Neurology, Karolinska University Hospital, Stockholm, Sweden.
Roberto AcamporaDepartment of Neurology and Stroke Unit, Ospedale del Mare Hospital, Naples, Italy.
Alberto NegroDepartment of Neurology and Stroke Unit, Ospedale del Mare Hospital, Naples, Italy.
Theodoros Karapanayiotides2nd Department of Neurology, Aristotle University of Thessaloniki, School of Medicine, AHEPA University Hospital, Greece.
Shadi YaghiDepartment of Neurology, Brown University, Providence, RI, USA.
Anna RevertHospital del Mar, Faculty of Medicine and Life Sciences, Pompeu Fabra University Barcelona, Spain.
Elisa Cuadrado GodiaHospital del Mar, Faculty of Medicine and Life Sciences, Pompeu Fabra University Barcelona, Spain.
Sebastian Garcia-MadronaDepartment of Neurology and Stroke Center, University Hospital Ramón y Cajal, Madrid, Spain.
Paolino La SpinaTranslational Molecular Medicine and Surgery 36th Cycle, Department of BIOMORF, Stroke Unit, Department of Clinical and Experimental Medicine, University Hospital G. Martino, Messina, Italy.
Francesco GrilloTranslational Molecular Medicine and Surgery 36th Cycle, Department of BIOMORF, Stroke Unit, Department of Clinical and Experimental Medicine, University Hospital G. Martino, Messina, Italy.
Fabrizio GiammelloTranslational Molecular Medicine and Surgery 36th Cycle, Department of BIOMORF, Stroke Unit, Department of Clinical and Experimental Medicine, University Hospital G. Martino, Messina, Italy.ORCID 0000-0002-2828-1305
Thanh N NguyenNeurology, Boston Medical Center, MA, USA.ORCID 0000-0002-2810-1685
Mohamad AbdalkaderRadiology, Boston Medical Center, MA, USA.
Alina ButureMater Misericordiae University Hospital, Dublin, Ireland.
Maria Sofia CotelliNeurology Unit ASST Valcamonica, Esine, Brescia, Italy.
Nicolas RaposoDepartment of Neurology, University Hospital of Toulouse, Toulouse, France.ORCID 0000-0002-9152-4445
Georgios TsivgoulisSecond Department of Neurology, National & Kapodistrian University of Athens, School of Medicine, "Attikon University Hospital", Athens, Greece.ORCID 0000-0002-0640-3797
Paolo CandelaresiNeurology and Stroke Unit, Cardarelli Hospital, Naples, Italy.ORCID 0000-0003-2477-840X
Antonio CiacciarelliNeurology Division, Santa Maria Goretti Hospital, Latina, Italy.ORCID 0000-0003-3282-4672
Joshua MbrohDepartment of Neurology & Stroke, University Hospital Tuebingen, Eberhard-Karls University, Tuebingen, Germany.ORCID 0000-0002-0108-9161
Tatiana BatenkovaSverdlovsk Regional Clinical Hospital No. 1, Yekaterinburg, Russia.ORCID 0009-0003-5058-063X
Pasquale ScoppettuoloNeurology Department, Cliniques Universitaires Saint Luc, Université Catholique de Louvain (UCL), Brussels, Belgium.
Marialuisa ZeddeNeurology Unit, Stroke Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Rosario PascarellaNeuroradiology Unit, Azienda Unità Sanitaria-IRCCS di Reggio Emilia, Italy.
Kateryna AntonenkoDepartment of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Espen S KristoffersenDepartment of Neurology, Akershus University Hospital, Lorenskog, Norway.ORCID 0000-0002-8999-5424
Johanna A Kremer HovingaDepartment of Hematology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Katarina JoodDepartment of Neurology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Diana Aguiar de SousaLisbon Central University Hospital and Faculdade de Medicina da Universidade de Lisboa, Portugal.ORCID 0000-0002-6702-7924
Sven PoliDepartment of Neurology & Stroke, University Hospital Tuebingen, Eberhard-Karls University, Tuebingen, Germany.
Turgut TatlisumakDepartment of Neurology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Jukka PutaalaNeurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Jonathan M CoutinhoDepartment of Neurology, Amsterdam UMC, location University of Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0002-8284-982X
José M FerroCentro de Estudos Egas Moniz, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.
Marcel ArnoldDepartment of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Mirjam R HeldnerDepartment of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
University of Bern · CHAmsterdam Neuroscience · NLSahlgrenska University Hospital · SEUniversity of Messina · ITAga Khan University · PKAzienda Sanitaria Unità Locale di Reggio Emilia · ITBoston Medical Center · USChristian Medical College, Vellore · INOspedale D. Cotugno · ITUniversitat Pompeu Fabra · ESUniversity of Lisbon · PTAkershus University Hospital · NOAristotle University of Thessaloniki · GRBrown University · USCliniques Universitaires Saint-Luc · BEHertie Institute for Clinical Brain Research · DEInstitute of Chemistry · MDInstituto Cajal · ESKarolinska University Hospital · SEMater Misericordiae University Hospital · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPrevious reports and meta-analyses derived from small case series reported a mortality rate of up to 40% in patients with coronavirus disease 2019 associated cerebral venous thrombosis (COVID-CVT). We assessed the clinical characteristics and outcomes in an international cohort of patients with COVID-CVT. PATIENTS AND

methodsThis was a registry study of consecutive COVID-CVT patients diagnosed between March 2020 and March 2023. Data collected by the International Cerebral Venous Thrombosis Consortium from patients with CVT diagnosed between 2017 and 2018 served as a comparison. Outcome analyses were adjusted for age and sex.

resultsWe included 70 patients with COVID-CVT from 23 hospitals in 15 countries and 206 controls from 14 hospitals in 13 countries. The proportion of women was smaller in the COVID-CVT group (50% vs 68%,

conclusionIn contrast to previous studies, the in-hospital mortality rate and functional outcomes during follow-up did not differ between COVID-CVT patients and the pre-COVID-19 controls.

Indexed as

COVID-19Intracranial ThrombosisRegistriesVenous ThrombosisAdultAgedFemaleHospital MortalityHumansLength of StayMaleMiddle AgedSARS-CoV-2Cerebral venous thrombosisCOVID-19stroke

Identifiers

PMID38572798
PMCPMC11418515
OpenAlexW4393934947

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.