Evidence map›Paper›PMID 38572666›Full record

ReviewClinical and translational medicine2024

Standardisation is the key to the sustained, rapid and healthy development of stem cell-based therapy.

Jing Zhang, Moran Suo, Jinzuo Wang, Xin Liu, Huagui Huang, Kaizhong Wang, Xiangyan Liu, Tianze Sun, Zhonghai Li, Jing Liu

Open access · goldAbstract readReview
In one paragraph

Review in Clinical and translational medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Jing ZhangDepartment of Orthopedics, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, China.
Moran SuoDepartment of Orthopedics, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, China.
Jinzuo WangDepartment of Orthopedics, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, China.
Xin LiuDepartment of Orthopedics, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, China.
Huagui HuangDepartment of Orthopedics, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, China.
Kaizhong WangDepartment of Orthopedics, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, China.
Xiangyan LiuDepartment of Orthopedics, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, China.
Tianze SunDepartment of Orthopedics, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, China.
Zhonghai LiDepartment of Orthopedics, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, China.ORCID 0000-0003-4735-1193
Jing LiuStem Cell Clinical Research Center, National Joint Engineering Laboratory, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, China.
Dalian Medical University · CNDalian University of Foreign Languages · CN

Funding

Natural Science Foundation of Liaoning Province 2022-MS-322Science and Technology Innovation Foundation of Dalian 2022JJ12SN045
6 · The paper itself

Abstract

backgroundStem cell-based therapy (SCT) is an important component of regenerative therapy that brings hope to many patients. After decades of development, SCT has made significant progress in the research of various diseases, and the market size has also expanded significantly. The transition of SCT from small-scale, customized experiments to routine clinical practice requires the assistance of standards. Many countries and international organizations around the world have developed corresponding SCT standards, which have effectively promoted the further development of the SCT industry.

methodsWe conducted a comprehensive literature review to introduce the clinical application progress of SCT and focus on the development status of SCT standardization.

resultsWe first briefly introduced the types and characteristics of stem cells, and summarized the current clinical application and market development of SCT. Subsequently, we focused on the development status of SCT-related standards as of now from three levels: the International Organization for Standardization (ISO), important international organizations, and national organizations. Finally, we provided perspectives and conclusions on the significance and challenges of SCT standardization.

conclusionsStandardization plays an important role in the sustained, rapid and healthy development of SCT.

Indexed as

Stem Cell TransplantationHumansReference Standardsclinical applicationregenerative medicinestandardisationstem cell therapy

Identifiers

PMID38572666
PMCPMC10993161
OpenAlexW4393948769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.