Evidence map›Paper›PMID 38572641›Full record

ArticleCirculation. Heart failure2024

Changes in Cardiac Function Following Fulminant Myocarditis.

Koshiro Kanaoka, Kenji Onoue, Satoshi Terasaki, Michikazu Nakai, Yoshitaka Iwanaga, Yoshihiro Miyamoto, Yoshihiko Saito

Abstract read
In one paragraph

Article in Circulation. Heart failure, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Koshiro KanaokaDepartment of Cardiovascular Medicine, Nara Medical University, Kashihara, Japan (K.K., K.O., S.T., Y.S.).ORCID 0000-0001-7900-7835
Kenji OnoueDepartment of Cardiovascular Medicine, Nara Medical University, Kashihara, Japan (K.K., K.O., S.T., Y.S.).ORCID 0000-0003-3233-4913
Satoshi TerasakiDepartment of Cardiovascular Medicine, Nara Medical University, Kashihara, Japan (K.K., K.O., S.T., Y.S.).ORCID 0000-0003-2345-0808
Michikazu NakaiDepartment of Medical and Health Information Management (K.K., M.N., Y.I.), National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.ORCID 0000-0003-2240-1510
Yoshitaka IwanagaDepartment of Medical and Health Information Management (K.K., M.N., Y.I.), National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.ORCID 0000-0002-1391-2864
Yoshihiro MiyamotoOpen Innovation Center (Y.M.), National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.ORCID 0000-0002-1337-0508
Yoshihiko SaitoDepartment of Cardiovascular Medicine, Nara Medical University, Kashihara, Japan (K.K., K.O., S.T., Y.S.).ORCID 0000-0001-5574-3571

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe natural history of myocardial dysfunction in patients with fulminant myocarditis is poorly understood. This study aims to evaluate changes in cardiac function in patients with fulminant myocarditis using a nationwide registry in Japan.

methodsThis retrospective cohort study included patients with biopsy-proven fulminant myocarditis and available for left ventricular ejection fraction (LVEF). We described the LVEF on admission, at discharge, and 1 year after discharge. We divided patients into 2 groups based on LVEF at discharge (reduced ejection fraction of <50% or preserved ejection fraction of ≥50%) and analyzed changes in LVEF and prognosis according to groups.

resultsWe included 214 patients (the median [first-third quartiles] age of the cohort was 48 [35-62] years, and 63 [38%] were female). Of 153 patients available for LVEF at 1 year, the median (first-third quartiles) LVEF increased from 33% (21-45%) on admission to 59% (49-64%) at discharge and further to 61% (55-66%) at 1 year. Of 153 patients, 45 (29%) and 22 (14%) had LVEF <50% at discharge and at 1 year, respectively. Comparisons between patients with LVEF <50% and those with LVEF ≥50% demonstrated that the former group had a higher adjusted probability of death or heart transplantation (hazard ratio, 8.19 [95% CI, 2.13-31.5];

conclusionsSome patients with fulminant myocarditis had left ventricular dysfunction in the chronic phase. Patients with reduced left ventricular function at discharge had a worse prognosis than those with preserved left ventricular function. REGISTRATION: URL: https://upload.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000045352; Unique identifier: UMIN000039763.

Indexed as

Heart FailureMyocarditisVentricular Dysfunction, LeftAdultFemaleHumansMaleMiddle AgedPrognosisRetrospective StudiesStroke VolumeVentricular Function, Leftbiopsymyocarditisprognosisventricular function, left

Identifiers

PMID38572641
PMCPMC11008446

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.