ArticleClinical kidney journal2024
Ionized and total magnesium levels in patients with chronic kidney disease: associated factors and outcomes.
Article in Clinical kidney journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- Magnesium supplements, sleep quality, and nocturnal leg cramps: a combination of cross-sectional and prospective studies.European journal of nutrition · 2026Article
- Association between low magnesium status and new-onset dementia in the general population: a propensity score-matched cohort study.Frontiers in nutrition · 2026Article
- The impact of low serum and dialysate magnesium levels on clinical outcomes in peritoneal dialysis patients: a literature review.BMC nephrology · 2025Review
- Dysmagnesemia in the ICU: A Comparative Analysis of Ionized and Total Magnesium Levels and Their Clinical Associations.Metabolites · 2025Article
- The importance of measuring the levels of ionized magnesium in the blood in critically ill patients.Journal of medical biochemistry · 2025Article
- Ionized and total magnesium levels and health outcomes in patients with type 2 diabetes mellitus.Scientific reports · 2025Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The association between hypo- and/or hypermagnesaemia and cardiovascular (CV) outcomes or mortality has shown conflicting results in chronic kidney disease (CKD) and has been conducted on total magnesium (tMg) levels. Thus, the objectives of the present study were to (i) describe the serum ionized Mg (iMg) concentration in patients at various CKD stages, (ii) measure the correlation between iMg and tMg concentrations, (iii) identify their associated factors and (iv) determine whether serum tMg and/or iMg concentrations are associated with major adverse cardiovascular events (MACE) and mortality before kidney replacement therapy in CKD patients. Methods: Chronic Kidney Disease-Renal Epidemiology and Information Network (CKD-REIN) is a prospective cohort of CKD patients with an estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m Results: Of the 2419 included patients, median age was 68 years, and the mean eGFR was 34.8 mL/min/1.73 m Conclusions: Our analysis of a large cohort of patients with moderate-to-advanced CKD demonstrated that individuals with higher serum tMg concentrations, although still within the normal range, had a greater likelihood of MACE and mortality. However, serum iMg levels were not associated with these outcomes.
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