Evidence map›Paper›PMID 38572485›Full record

ArticleFrontiers in cell and developmental biology2024

Dedifferentiated early postnatal lung myofibroblasts redifferentiate in adult disease.

Rachana R Chandran, Taylor S Adams, Inamul Kabir, Eunate Gallardo-Vara, Naftali Kaminski, Brigitte N Gomperts, Daniel M Greif

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Rachana R ChandranYale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Medicine, Yale University School of Medicine, New Haven, CT, United States.
Taylor S AdamsSection of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, United States.
Inamul KabirYale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Medicine, Yale University School of Medicine, New Haven, CT, United States.
Eunate Gallardo-VaraYale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Medicine, Yale University School of Medicine, New Haven, CT, United States.
Naftali KaminskiSection of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, United States.
Brigitte N GompertsDivision of Pulmonary and Critical Care Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States.
Daniel M GreifYale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Medicine, Yale University School of Medicine, New Haven, CT, United States.
Yale University · USBroad Center · USUniversity of California, Los Angeles · US

Funding

Novel vascular smooth muscle cell progenitors in development and diseaseR35HL150766 · NHLBI · YALE UNIVERSITY · PI Daniel Greif · 2020 to 2026
$7.0M
Epigenetic-mediated Notch pathway activation promotes elastin aortopathyR01HD110059 · NICHD · YALE UNIVERSITY · PI Daniel Greif, Kathleen Ann Martin · 2023 to 2026
$2.6M
Smooth muscle progenitors in vascular remodelingR01HL133016 · NHLBI · YALE UNIVERSITY · PI GREIF, DANIEL · 2016 to 2019
$1.7M
Pathological arterial muscularization and the role of integrinsR01HL125815 · NHLBI · YALE UNIVERSITY · PI GREIF, DANIEL · 2015 to 2018
$1.7M
Mural cell TGF-beta-mediated signaling and neonatal intracerebral hemorrhageR21NS088854 · NINDS · YALE UNIVERSITY · PI GREIF, DANIEL · 2014 to 2015
$458k
Myofibroblasts in pulmonary fibrosis: origin, clones and KLF4F32HL132532 · NHLBI · YALE UNIVERSITY · PI RADHAMANI CHANDRAN, RACHANA · 2016 to 2018
$174k
NHLBI NIH HHS F32 HL132532NHLBI NIH HHS R01 HL125815NHLBI NIH HHS R01 HL133016NHLBI NIH HHS R35 HL150766NICHD NIH HHS R01 HD110059NINDS NIH HHS R21 NS088854
6 · The paper itself

Abstract

Alveolarization ensures sufficient lung surface area for gas exchange, and during bulk alveolarization in mice (postnatal day [P] 4.5-14.5), alpha-smooth muscle actin (SMA)

Indexed as

alveolarizationfate mappinghypoxialung fibrosislung myofibroblastspulmonary hypertension

Identifiers

PMID38572485
PMCPMC10987733
OpenAlexW4393015034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.