Evidence map›Paper›PMID 38572358›Full record

ArticleFrontiers in bioengineering and biotechnology2024

Development of high-efficiency superparamagnetic drug delivery system with MPI imaging capability.

Shi Bai, Xiao-Dan Zhang, Yu-Qi Zou, Yu-Xi Lin, Zhi-Yao Liu, Ke-Wen Li, Ping Huang, Takashi Yoshida, Yi-Li Liu, Ming-Shan Li and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Shi BaiDepartment of Information Engineering, Shenyang University of Technology, Shenyang, China.
Xiao-Dan ZhangDepartment of Information Engineering, Shenyang University of Technology, Shenyang, China.
Yu-Qi ZouDepartment of Information Engineering, Shenyang University of Technology, Shenyang, China.
Yu-Xi LinDepartment of Information Engineering, Shenyang University of Technology, Shenyang, China.
Zhi-Yao LiuDepartment of Information Engineering, Shenyang University of Technology, Shenyang, China.
Ke-Wen LiDepartment of Information Engineering, Shenyang University of Technology, Shenyang, China.
Ping HuangDepartment of Information Engineering, Shenyang University of Technology, Shenyang, China.
Takashi YoshidaDepartment of Electrical Engineering, Kyushu University, Fukuoka, Japan.
Yi-Li LiuDepartment of Urology, Fourth Affiliated Hospital of China Medical University, Shenyang, China.
Ming-Shan LiDepartment of Urology, Fourth Affiliated Hospital of China Medical University, Shenyang, China.
Wei ZhangDepartment of Oncology, General Hospital of Northern Theater Command, Shenyang, China.
Xiao-Ju WangDepartment of Foreign Languages, Liaoning Vocational and Technical College of Economics, Shenyang, China.
Min ZhangFirst Affiliated Hospital, China Medical University, Shenyang, China.
Cheng DuDepartment of Oncology, General Hospital of Northern Theater Command, Shenyang, China.
Shenyang University of Technology · CNChina Medical University · CNGeneral Hospital of Shenyang Military Region · CNKyushu University · JPLiaoning Jianzhu Vocational University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, a high-efficiency superparamagnetic drug delivery system was developed for preclinical treatment of bladder cancer in small animals. Two types of nanoparticles with magnetic particle imaging (MPI) capability, i.e., single- and multi-core superparamagnetic iron oxide nanoparticles (SPIONs), were selected and coupled with bladder anti-tumor drugs by a covalent coupling scheme. Owing to the minimal particle size, magnetic field strengths of 270 mT with a gradient of 3.2 T/m and 260 mT with a gradient of 3.7 T/m were found to be necessary to reach an average velocity of 2 mm/s for single- and multi-core SPIONs, respectively. To achieve this, a method of constructing an

Indexed as

drug deliverymagnetic drug targetingmagnetic particle imagingsuperparamagnetic iron oxide nanoparticlestumor therapy

Identifiers

PMID38572358
PMCPMC10987818
OpenAlexW4393012581

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.