Evidence map›Paper›PMID 38572268›Full record

ArticleBrain communications2024

Volumetric analysis of hippocampal subregions and subfields in left and right semantic dementia.

Arenn F Carlos, Stephen D Weigand, Joseph R Duffy, Heather M Clark, Rene L Utianski, Mary M Machulda, Hugo Botha, Nha Trang Thu Pham, Val J Lowe, Christopher G Schwarz and 2 more

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Arenn F CarlosDepartment of Neurology, Mayo Clinic, Rochester, MN 55905USA.ORCID https://orcid.org/0000-0002-2100-5033
Stephen D WeigandDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, MN 55905USA.
Joseph R DuffyDepartment of Neurology, Mayo Clinic, Rochester, MN 55905USA.ORCID https://orcid.org/0000-0001-8206-3432
Heather M ClarkDepartment of Neurology, Mayo Clinic, Rochester, MN 55905USA.
Rene L UtianskiDepartment of Neurology, Mayo Clinic, Rochester, MN 55905USA.
Mary M MachuldaDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905USA.
Hugo BothaDepartment of Neurology, Mayo Clinic, Rochester, MN 55905USA.ORCID https://orcid.org/0000-0003-4390-685X
Nha Trang Thu PhamDepartment of Radiology, Mayo Clinic, Rochester, MN 55905USA.
Val J LoweDepartment of Radiology, Mayo Clinic, Rochester, MN 55905USA.
Christopher G SchwarzDepartment of Radiology, Mayo Clinic, Rochester, MN 55905USA.ORCID https://orcid.org/0000-0002-1466-8357
Jennifer L WhitwellDepartment of Radiology, Mayo Clinic, Rochester, MN 55905USA.ORCID https://orcid.org/0000-0001-6914-1563
Keith A JosephsDepartment of Neurology, Mayo Clinic, Rochester, MN 55905USA.ORCID https://orcid.org/0000-0003-2930-8634
Mayo Clinic · USMayo Clinic in Florida · US

Funding

PIB PET Scanning in Speech and Language Based DementiasR01DC010367 · NIDCD · MAYO CLINIC ROCHESTER · PI JOSEPHS, KEITH A · 2010 to 2014
$1.7M
Assessment of hyperphosphorylated tau PET binding in primary progressive aphasiaR21NS094684 · NINDS · MAYO CLINIC ROCHESTER · PI JOSEPHS, KEITH A · 2016 to 2017
$417k
NIDCD NIH HHS R01 DC010367NINDS NIH HHS R21 NS094684
6 · The paper itself

Abstract

Two variants of semantic dementia are recognized based on the laterality of temporal lobe involvement: a left-predominant variant associated with verbal knowledge impairment and a right-predominant variant associated with behavioural changes and non-verbal knowledge loss. This cross-sectional clinicoradiologic study aimed to assess whole hippocampal, subregion, and/or subfield volume loss in semantic dementia versus controls and across its variants. Thirty-five semantic dementia participants and 15 controls from the Neurodegenerative Research Group at Mayo Clinic who had completed 3.0-T volumetric magnetic resonance imaging and

Indexed as

anterior temporal polehippocampal segmentationright temporal semantic dementiasemantic variant PPAtemporopolar syndromes

Identifiers

PMID38572268
PMCPMC10988847
OpenAlexW4393158715

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.