Evidence map›Paper›PMID 38572112›Full record

ArticleActa pharmaceutica Sinica. B2024

Ginsenoside modified lipid-coated perfluorocarbon nanodroplets: A novel approach to reduce complement protein adsorption and prolong

Jie Zhou, Binyang Gao, Huan Zhang, Rui Yang, Jianbo Huang, Xin Li, Yi Zhong, Yan Wang, Xiaoxia Zhu, Yan Luo and 1 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta pharmaceutica Sinica. B, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Jie ZhouUltrasound Department of West China Hospital, Sichuan University, Chengdu 610041, China.
Binyang GaoUltrasound Department of West China Hospital, Sichuan University, Chengdu 610041, China.
Huan ZhangUltrasound Department of West China Hospital, Sichuan University, Chengdu 610041, China.
Rui YangUltrasound Department of West China Hospital, Sichuan University, Chengdu 610041, China.
Jianbo HuangUltrasound Department of West China Hospital, Sichuan University, Chengdu 610041, China.
Xin LiWest China Washington Mitochondria and Metabolism Research Center, West China Hospital, Sichuan University, Chengdu 610041, China.
Yi ZhongWest China Washington Mitochondria and Metabolism Research Center, West China Hospital, Sichuan University, Chengdu 610041, China.
Yan WangResearch Core Facilities of West China Hospital, Sichuan University, Chengdu 610041, China.
Xiaoxia ZhuUltrasound Department of West China Hospital, Sichuan University, Chengdu 610041, China.
Yan LuoUltrasound Department of West China Hospital, Sichuan University, Chengdu 610041, China.
Feng YanUltrasound Department of West China Hospital, Sichuan University, Chengdu 610041, China.
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipid-coated perfluorocarbon nanodroplets (lp-NDs) hold great promise in bio-medicine as vehicles for drug delivery, molecular imaging and vaccine agents. However, their clinical utility is restricted by limited targeted accumulation, attributed to the innate immune system (IIS), which acts as the initial defense mechanism in humans. This study aimed to optimize lp-ND formulations to minimize non-specific clearance by the IIS. Ginsenosides (Gs), the principal components of

Indexed as

Complement C3Complement systemGinsenoside lipid-coated perfluorocarbon nanodropletsInnate immune systemLipid-coated perfluorocarbon nanodropletsMononuclear phagocytic systemPhagocytosisProtein corona

Identifiers

PMID38572112
PMCPMC10985128
OpenAlexW4388705914

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.