Evidence map›Paper›PMID 38571986›Full record

ArticleJournal of pediatric intensive care2024

Antipsychotic Drug Prescription in Pediatric Intensive Care Units: A 10-Year U.S. Retrospective Database Study.

Kate Madden, Michael Wolf, Robert C Tasker, Janet Figueroa, Courtney McCracken, Matt Hall, Pradip Kamat

Open access · hybridAbstract read
In one paragraph

Article in Journal of pediatric intensive care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Analgesia and sedation practice in children in intensive care in Australia and New Zealand: A survey.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Kate MaddenDepartment of Anesthesiology, Critical Care, and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts, United States.ORCID 0000-0002-4905-2640
Michael WolfDepartment of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, United States.
Robert C TaskerDepartment of Anesthesiology, Critical Care, and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts, United States.
Janet FigueroaDepartment of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, United States.
Courtney McCrackenDepartment of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, United States.
Matt HallChildren's Hospital Association, Lenexa, Kansas, United States.
Pradip KamatDepartment of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, United States.
Emory University · USBoston Children's Hospital · USChildren's Hospital Association · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Delirium recognition during pediatric critical illness may result in the prescription of antipsychotic medication. These medications have unclear efficacy and safety. We sought to describe antipsychotic medication use in pediatric intensive care units (PICUs) contributing to a U.S. national database. This study is an analysis of the Pediatric Health Information System Database between 2008 and 2018, including children admitted to a PICU aged 0 to 18 years, without prior psychiatric diagnoses. Antipsychotics were given in 16,465 (2.3%) of 706,635 PICU admissions at 30 hospitals. Risperidone (39.6%), quetiapine (22.1%), and haloperidol (20.8%) were the most commonly used medications. Median duration of prescription was 4 days (interquartile range: 2-11 days) for atypical antipsychotics, and haloperidol was used a median of 1 day (1-3 days). Trend analysis showed quetiapine use increased over the study period, whereas use of haloperidol and chlorpromazine (typical antipsychotics) decreased (

Indexed as

antipsychoticdeliriumpediatric critical care

Identifiers

PMID38571986
PMCPMC10987219
OpenAlexW3209056721

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.