Evidence map›Paper›PMID 38571403›Full record

ReviewThe international journal of lower extremity wounds2026

M.O.I.S.T. Concept for the Local Therapy of Chronic Wounds: An International Update.

Joachim Dissemond, Paul Chadwick, Dot Weir, Paulo Alves, Kirsi Isoherranen, José Luis Lázaro Martínez, Terry Swanson, Andrea Gledhill, Matthew Malone

Abstract readReview
In one paragraph

Review in The international journal of lower extremity wounds, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Dextran-based stimuli-responsive hydrogels for smart dressings in wound healing.Journal of materials science. Materials in medicine · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Joachim DissemondDepartment of Dermatology, Venerology and Allergology, University of Essen, Essen, Germany.ORCID 0000-0003-3893-328X
Paul ChadwickBirmingham City University, Birmingham, UK.
Dot WeirSaratoga Hospital Center for Wound Healing and Hyperbaric Medicine, Saratoga Springs, NY, USA.
Paulo AlvesUniversidade Católica Portuguesa, Institute of Health Sciences - Wounds Research Lab, Lisboa, Portugal.
Kirsi IsoherranenDepartment of Dermatology and Allergology, University of Helsinki and Inflammation center, Helsinki University Hospital and Helsinki University, Helsinki, Finland.ORCID 0000-0002-0253-2567
José Luis Lázaro MartínezDiabetic Foot Unit, Universidad Complutense de Madrid, Madrid, Spain.ORCID 0000-0001-6110-0265
Terry SwansonWound Education Research Consultancy, Warrnambool, Victoria, Australia.
Andrea GledhillDepartment of Podiatric Surgery, Trauma and Orthopaedics, Great Western Hospital NHSFT, Swindon, UK.ORCID 0009-0004-3168-7076
Matthew MaloneResearch and Development, Molnlycke Healthcare AB, Gothenburg, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic wounds remain a significant clinical challenge both for those affected and for healthcare systems. The treatment is often comprised and complex. All patients should receive wound care that is integrated into a holistic approach involving local management that addresses the underlying etiology and provides for gold standard therapy to support healing, avoid complications and be more cost effective. There have been significant advances in medicine over the last few decades. The development of new technologies and therapeutics for the local treatment of wounds is also constantly increasing. To help standardize clinical practice with regard to the multitude of wound products, the M.O.I.S.T. concept was developed by a multidisciplinary expert group. The M stands for moisture balance, O for oxygen balance, I for infection control, S for supporting strategies, and T for tissue management. Since the M.O.I.S.T. concept, which originated in the German-speaking countries, is now intended to provide healthcare professionals with an adapted instrument to be used in clinical practice, and a recent update to the concept has been undertaken by a group of interdisciplinary experts to align it with international standards. The M.O.I.S.T. concept can now be used internationally both as an educational tool and for the practical implementation of modern local treatment concepts for patients with chronic wounds and can also be used in routine clinical practice.

Indexed as

Wound HealingWounds and InjuriesChronic DiseaseHumanschronic woundslocal therapyM.O.I.S.T. conceptwound healingwound treatment

Identifiers

PMID38571403
PMCPMC13191081

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.