Evidence map›Paper›PMID 38571343›Full record

ReviewMicroRNA (Shariqah, United Arab Emirates)2024

Role of miRNAs in Brain Development.

Himanshu Sharma, Monika Kaushik, Priyanka Goswami, Sanakattula Sreevani, Ananya Chakraborty, Sumel Ashique, Radheshyam Pal

Abstract readReview
PubMed Publisher
In one paragraph

Review in MicroRNA (Shariqah, United Arab Emirates), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

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  15. Frontiers in cell and developmental biology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Himanshu SharmaTeerthanker Mahaveer College of Pharmacy, Teerthanker Mahaveer University, Moradabad (UP), 244001, India.
Monika KaushikAmity Institute of Pharmacy, Amity University Gwalior, 474005, Madhya Pradesh, India.
Priyanka GoswamiDepartment of Pharmacognosy, Maharashtra Educational Society's H. K. College of Pharmacy, Mumbai, Maharashtra, 400102, India.
Sanakattula SreevaniDepartment of Pharmacology, Vivekananda College of Pharmacy, Rajajinagar, Bengaluru, Karnataka, 560055, India.
Ananya ChakrabortyDepartment of Biotechnology, Maulana Abul Kalam Azad University of Technology, West Bengal, 700064, India.
Sumel AshiqueDepartment of Pharmaceutical Sciences, Bengal College of Pharmaceutical Sciences & Research, Durgapur, 713212, West Bengal, India.ORCID 0000-0003-4362-2830
Radheshyam PalDepartment of Pharmaceutical Sciences, Bengal College of Pharmaceutical Sciences & Research, Durgapur, 713212, West Bengal, India.
Indian Education Society's V. N. Sule Guruji English Medium School · INMaulana Abul Kalam Azad University of Technology, West Bengal · INSwami Vivekanand College of Pharmacy · INTeerthanker Mahaveer University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-coding RNAs that are small in size, called microRNAs (miRNAs), exert a consequence in neutralizing gene activity after transcription. The nervous system is a massively expressed organ, and an expanding body of research reveals the vital functions that miRNAs play in the brain's growth and neural activity. The significant benefit of miRNAs on the development of the central nervous system is currently shown through new scientific methods that concentrate on targeting and eradicating vital miRNA biogenesis pathways the elements involving Dicer and DGCR8. Modulation of miRNA has been associated with numerous essential cellular processes on neural progenitors, like differentiation, proliferation, and destiny determination. Current research discoveries that emphasize the significance of miRNAs in the complex process of brain development are included in this book. The miRNA pathway plays a major role in brain development, its operational dynamics, and even diseases. Recent studies on miRNA-mediated gene regulation within neural discrepancy, the circadian period and synaptic remodeling are signs of this. We also discussed how these discoveries may affect our comprehension of the fundamental processes behind brain diseases, highlighting the novel therapeutic opportunities miRNAs provide for treating various human illnesses.

Indexed as

BrainMicroRNAsAnimalsCell DifferentiationGene Expression Regulation, DevelopmentalHumansNeurogenesisRibonuclease IIIRNA-Binding ProteinsDGCR8 protein, humanMicroRNAsRibonuclease IIIRNA-Binding Proteinsbiogenesisbio-markersbrain developmentbrain physiologymiR-17-92miR-9miRNAneurodegeneration.

Identifiers

PMID38571343
OpenAlexW4393943997

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.