Evidence map›Paper›PMID 38569927›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2024

Rare GPR37L1 Variants Reveal Potential Association between GPR37L1 and Disorders of Anxiety and Migraine.

Gerda E Breitwieser, Andrea Cippitelli, Yingcai Wang, Oliver Pelletier, Ridge Dershem, Jianning Wei, Lawrence Toll, Bianca Fakhoury, Gloria Brunori, Raghu Metpally and 3 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Gerda E BreitwieserCharles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, Florida.
Andrea CippitelliCharles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, Florida.
Yingcai WangCharles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, Florida.
Oliver PelletierCharles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, Florida.
Ridge DershemCharles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, Florida.
Jianning WeiCharles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, Florida.
Lawrence TollCharles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, Florida.
Bianca FakhouryCharles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, Florida.
Gloria BrunoriCharles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, Florida.
Raghu MetpallySonic Healthcare USA, Rye Brook, New York.
David J CareyGeisinger, Weis Center for Research, Danville, Pennsylvania.
Regeneron Genetics Center
Janet RobishawCharles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, Florida robishawj@ufl.edu.
Florida Atlantic University · US

Funding

MIXED NOP/MU COMPOUNDS AND THE INVOLVEMENT OF THEIR RECEPTORS IN ANALGESIAR01DA023281 · NIDA · TORREY PINES INST FOR MOLECULAR STUDIES · PI TOLL, LAWRENCE R · 2007 to 2021
$6.4M
An integrated approach to study GPCR variants associated with complex diseasesR01GM111913 · NIGMS · GEISINGER CLINIC · PI MIRSHAHI, TOORAJ, ROBISHAW, JANET D · 2015 to 2018
$2.1M
NIDA NIH HHS R01 DA023281NIGMS NIH HHS R01 GM111913
6 · The paper itself

Abstract

GPR37L1 is an orphan receptor that couples through heterotrimeric G-proteins to regulate physiological functions. Since its role in humans is not fully defined, we used an unbiased computational approach to assess the clinical significance of rare

Indexed as

Migraine DisordersReceptors, G-Protein-CoupledAnimalsAnxiety DisordersFemaleGenetic VariationHumansMaleMiceMice, Inbred C57BLMice, KnockoutGPR37L1 protein, humanGpr37l1 protein, mouseReceptors, G-Protein-Coupleddisease associationgenetic variationneurobiologyreceptorsignal transduction

Identifiers

PMID38569927
PMCPMC11089846
OpenAlexW4393864273

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.