Evidence map›Paper›PMID 38569912›Full record

ArticleInternal medicine (Tokyo, Japan)2024

Plain Computed Tomography for Differentiating Neoplastic and Non-neoplastic Pedunculated Gallbladder Polyps.

Fumisato Kozakai, Takahisa Ogawa, Toshitaka Sakai, Shinsuke Koshita, Yoshihide Kanno, Hiroaki Kusunose, Keisuke Yonamine, Kazuaki Miyamoto, Haruka Okano, Yuto Matsuoka and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Fumisato KozakaiDepartment of Gastroenterology, Sendai City Medical Center, Japan.
Takahisa OgawaDepartment of Gastroenterology, Sendai City Medical Center, Japan.
Toshitaka SakaiDepartment of Gastroenterology, Sendai City Medical Center, Japan.
Shinsuke KoshitaDepartment of Gastroenterology, Sendai City Medical Center, Japan.
Yoshihide KannoDepartment of Gastroenterology, Sendai City Medical Center, Japan.
Hiroaki KusunoseDepartment of Gastroenterology, Sendai City Medical Center, Japan.
Keisuke YonamineDepartment of Gastroenterology, Sendai City Medical Center, Japan.
Kazuaki MiyamotoDepartment of Gastroenterology, Sendai City Medical Center, Japan.
Haruka OkanoDepartment of Gastroenterology, Sendai City Medical Center, Japan.
Yuto MatsuokaDepartment of Gastroenterology, Sendai City Medical Center, Japan.
Kento HosokawaDepartment of Gastroenterology, Sendai City Medical Center, Japan.
Hidehito SumiyaDepartment of Gastroenterology, Sendai City Medical Center, Japan.
Reiji SugitaDepartment of Radiology, Sendai City Medical Center, Japan.
Kei ItoDepartment of Gastroenterology, Sendai City Medical Center, Japan.
Sendai Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective Surgery is recommended for large pedunculated gallbladder polyps (PGPs), which measure 10 mm or more in size, because they tend to be neoplastic polyps (NPs), such as adenomas and adenocarcinomas. However, after resection, they are often found to be non-neoplastic polyps (non-NPs). This study aimed to evaluate the usefulness of plain computed tomography (CT) in distinguishing NPs from non-NPs. Methods Of the 80 patients who underwent cholecystectomy for PGPs ≥10 mm between January 2008 and February 2021, 46 who underwent plain and contrast-enhanced CT (CE-CT) before resection were included in this study. We retrospectively assessed the polyp detection rate (PDR) using CT and calculated the difference in the CT values between PGPs and the surrounding bile. Results Twenty-one patients had NPs (12 adenomas, 5 carcinomas in adenoma, and 4 adenocarcinomas). The others were non-NPs (24 cholesterol polyps and one hyperplastic polyp). The PDR using plain CT was significantly higher in the NP group than in the non-NP group (38% (8/21) vs. 0% (0/25), p <0.01). The sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy of NPs were 38%, 100%, 100%, 66%, and 72%, respectively. The difference in the CT values between PGPs and the surrounding bile was significantly larger in the NP group than in the non-NP group (14.12 ± 11.38 HU, 5.04 ± 6.15 HU, p <0.01). Conclusions PGPs detected using plain CT had a high probability of being NPs. Plain CT is therefore considered to be useful for differentiating NPs from non-NPs.

Indexed as

Gallbladder NeoplasmsPolypsTomography, X-Ray ComputedAdenocarcinomaAdenomaAdultAgedAged, 80 and overCholecystectomyDiagnosis, DifferentialFemaleGallbladderGallbladder DiseasesHumansMaleMiddle Agedcholesterol polypgallbladder carcinomaneoplastic polyppedunculated gallbladder polypsplain computed tomography

Identifiers

PMID38569912
PMCPMC11637784
OpenAlexW4393395253

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.