ArticleJournal of atherosclerosis and thrombosis2024
Associations of Sedentary Behavior with Risks of Cardiovascular Disease Events among Chinese Adults.
Article in Journal of atherosclerosis and thrombosis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 3 citations in OpenAlex.
- Adiposity-Metabolic Discordance Identifies Cardiometabolically Heterogeneous Profiles in Normal-Weight Adults: A Cross-Sectional Study.Medical sciences (Basel, Switzerland) · 2026Article
- Bidirectional reallocations of sitting time, physical activity, and sleep in relation to risk of all-cause mortality and cardiovascular disease: An analysis of the Prospective Urban Rural Epidemiology (PURE)-China cohort study.Journal of sport and health science · 2026Article
- Latent profile analysis of health status and influencing factors among patients with coronary heart disease based on patient-reported outcomes.Frontiers in cardiovascular medicine · 2026Article
- Gout, Uric Acid, and Coronary Artery Disease.Journal of atherosclerosis and thrombosis · 2025Review
- Sedentary behavior mediates the association between weight-adjusted waist index and cardiovascular disease in patients with diabetes.PloS one · 2025Article
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Authors and funding
12 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsEvidence regarding the modification effects of age, sex, ethnicity, socioeconomic status, or weight status on the associations of sedentary behavior (SB) with cardiovascular diseases (CVDs) is limited. Moreover, the mechanisms for the associations also remain unclear. We aimed to investigate the possible influence of these factors on the associations of SB with CVD events and whether the associations are mediated by metabolic phenotypes.
methodsThis study included 42,619 participants aged 20-74 years, recruited from the Shanghai Suburban Adult Cohort and Biobank study. SB was assessed at baseline and integrated with health information systems to predict future CVD events. Cox proportional hazards models, interaction analyses, restricted cubic splines and causal mediation analyses were used for assessments.
resultsCompared to those with ＜3 h/d sedentary time, participants having SB ≥ 5 h/d had significantly higher risks of CVD (HR[95%CI]: 1.27[1.12-1.44]), coronary heart disease (CHD, 1.35[1.14-1.60]), and ischemic stroke (IS, 1.30[1.06-1.60]). The association of CHD was more pronounced in the retired individuals than their counterparts (1.45[1.20-1.76] versus 1.06[0.74-1.52], p
conclusionsHigher SB was associated with elevated risks of CVD events. The detrimental effect of SB on CHD risk was more pronounced among retired individuals. Moreover, HDL-C, TG and SUA partially mediated the relationships between SB and CVD events. Our findings may have implications for preventing and controlling CVD associated with SB.
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