SynthesisBMJ open2024
Internet-delivered transdiagnostic psychological treatments for individuals with depression, anxiety or both: a systematic review with meta-analysis of randomised controlled trials.
Synthesis in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Comparing Video-Based and Face-to-Face Psychotherapy: Systematic Review and Multilevel Meta-Analysis Across Mental Disorders.Journal of medical Internet research · 2026Pooled it
- Evaluation of Two Web-Based Interventions (REMOTION and Res-Up!) for Clients From Psychotherapy Waitlists in Routine Outpatient Psychotherapy (Therapy Online Plus-TOP): Randomized Controlled Trial.Journal of medical Internet research · 2026Trial
- A Randomized Controlled Trial Comparing Transdiagnostic Behavior Therapy and Disorder-Specific Psychotherapies in Veterans With Emotional Disorders.Behavior therapy · 2026Trial
- Internet-delivered unguided psychodynamic vs. cognitive behavior therapy for anxiety and depression symptoms: A large, full factorial randomized controlled trial on treatment length and peer support.Internet interventions · 2026Article
- Exploring Patients' Experiences in a Blended Transdiagnostic Group Treatment: Qualitative Study.JMIR human factors · 2026Article
- Efficacy of an internet-based version of the unified protocol for transdiagnostic treatment of emotional disorders in adolescents (iUP-A): A randomized active-controlled trial.Internet interventions · 2026Article
- Innovations to improve outcomes and uptake of psychotherapies for mental disorders: a state-of-the-art review.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026Article
- Examining an entirely self-guided transdiagnostic internet-delivered intervention 'in the wild': A randomised controlled trial for anxiety and depression with minimal inclusion criteria.Internet interventions · 2025Article
- Proof-of-concept for a randomized factorial design strategy to build a complex online support program for cancer survivors with psychiatric symptoms: the IN-FACT-0 feasibility trial.Journal of cancer survivorship : research and practice · 2025Article
- Attitudes Towards Digital Health Interventions in Germany: Findings From a Population-Based Representative Survey.Clinical psychology in Europe · 2025Article
- Transdiagnostic-focused apps for depression and anxiety: a meta-analysis.NPJ digital medicine · 2025Article
- Effectiveness of a blended group transdiagnostic treatment for emotional disorders: Study protocol for a randomized controlled trial.Internet interventions · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveDepression and anxiety are major public health problems. This study evaluated the effects of internet-delivered transdiagnostic psychological treatments for individuals with depression, anxiety, or both.
designSystematic review with meta-analysis. DATA SOURCES: Medline (Ovid), Cochrane Library (Wiley), the Web of Science Core Collection (Clarivate), and PsycInfo (EBSCO) were searched on 24 May 2021, with an update on 6 February 2023. ELIGIBILITY CRITERIA: Randomised controlled trials of internet-delivered transdiagnostic psychological treatments, open to both participants with primary depression and participants with primary anxiety. This review concerned all treatment frameworks, both guided and unguided formats and all age groups. DATA EXTRACTION AND SYNTHESIS: In random-effects meta-analysis, we estimated pooled effects on depression symptoms and anxiety in terms of Hedges'
resultsWe included 57 trials with 21 795 participants. Nine trials (16%) recruited exclusively from routine care, and three (5%) delivered treatment via video. For adults, large within-group reductions were seen in depression (
conclusionInternet-delivered transdiagnostic treatments for depression and anxiety show small-to-moderate added effects, varying by control condition. Research is needed regarding routine care, the video format, children and adolescents and older adults. PROSPERO REGISTRATION NUMBER: CRD42021243172.
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Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.