Evidence map›Paper›PMID 38569673›Full record

ArticleBMJ open2024

Inter-facility transfers for emergency obstetrical and neonatal care in rural Madagascar: a cost-effectiveness analysis.

Mara Anna Franke, Kim Nordmann, Anna Frühauf, Rinja Mitolotra Ranaivoson, Mahery Rebaliha, Zavaniarivo Rapanjato, Till Bärnighausen, Nadine Muller, Samuel Knauss, Julius Valentin Emmrich

Abstract read
In one paragraph

Article in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mara Anna FrankeCharité Center for Global Health, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID 0000-0001-7548-4423
Kim NordmannRWTH Aachen University, Aachen, Germany.
Anna FrühaufCharité Center for Global Health, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Rinja Mitolotra RanaivosonDoctors for Madagascar, Antananarivo, Madagascar.
Mahery RebalihaDoctors for Madagascar, Antananarivo, Madagascar.
Zavaniarivo RapanjatoDoctors for Madagascar, Antananarivo, Madagascar.
Till BärnighausenHeidelberg Institute of Global Health, Heidelberg University, Heidelberg, Germany.
Nadine MullerCharité Center for Global Health, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Samuel KnaussCharité Center for Global Health, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Julius Valentin EmmrichCharité Center for Global Health, Charité - Universitätsmedizin Berlin, Berlin, Germany julius.emmrich@charite.de.ORCID 0000-0002-3393-0840

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextThere is a substantial lack of inter-facility referral systems for emergency obstetrical and neonatal care in rural areas of sub-Saharan Africa. Data on the costs and cost-effectiveness of such systems that reduce preventable maternal and neonatal deaths are scarce.

settingWe aimed to determine the cost-effectiveness of a non-governmental organisation (NGO)-run inter-facility referral system for emergency obstetrical and neonatal care in rural Southern Madagascar by analysing the characteristics of cases referred through the intervention as well as its costs.

designWe used secondary NGO data, drawn from an NGO's monitoring and financial administration database, including medical and financial records. OUTCOME MEASURES: We performed a descriptive and a cost-effectiveness analysis, including a one-way deterministic sensitivity analysis.

results1172 cases were referred over a period of 4 years. The most common referral reasons were obstructed labour, ineffective labour and eclampsia. In total, 48 neonates were referred through the referral system over the study period. Estimated cost per referral was US$336 and the incremental cost-effectiveness ratio (ICER) was US$70 per additional life-year saved (undiscounted, discounted US$137). The sensitivity analysis showed that the intervention was cost-effective for all scenarios with the lowest ICER at US$99 and the highest ICER at US$205 per additional life-year saved. When extrapolated to the population living in the study area, the investment costs of the programme were US$0.13 per person and annual running costs US$0.06 per person.

conclusionsIn our study, the inter-facility referral system was a very cost-effective intervention. Our findings may inform policies, decision-making and implementation strategies for emergency obstetrical and neonatal care referral systems in similar resource-constrained settings.

Indexed as

Labor, ObstetricObstetricsCost-Benefit AnalysisCost-Effectiveness AnalysisFemaleHumansInfant, NewbornMadagascarPregnancyACCIDENT & EMERGENCY MEDICINEHealth economicsNEONATOLOGYOBSTETRICS

Identifiers

PMID38569673
PMCPMC11146390

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.