Evidence map›Paper›PMID 38569473›Full record

ArticleObesity facts2024

Association between Body Mass Index and Medication-Overuse Headache among Individuals with Migraine: A Cross-Sectional Study.

Huanxian Liu, Hongru Zhao, Kaiming Liu, Zhihua Jia, Ming Dong, Yingying Cheng, Yudan Lv, Kang Qu, Wei Gui, Jianjun Chen and 35 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Obesity facts, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

45 authors at 19 institutions in 1 country.

Huanxian LiuDepartment of Neurology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Hongru ZhaoDepartment of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Kaiming LiuDepartment of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Zhihua JiaDepartment of Neurology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Ming DongDepartment of Neurology and Neuroscience Center, The First Hospital of Jilin University, Changchun, China.
Yingying ChengDepartment of Neurology and Neuroscience Center, The First Hospital of Jilin University, Changchun, China.
Yudan LvDepartment of Neurology and Neuroscience Center, The First Hospital of Jilin University, Changchun, China.
Kang QuDepartment of Neurology and Neuroscience Center, The First Hospital of Jilin University, Changchun, China.
Wei GuiDepartment of Neurology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Jianjun ChenDepartment of Neurology, Lishui Municipal Central Hospital, Lishui, China.
Dan ZhangDepartment of Neurology, Sir Run Run Shaw Hospital, Hangzhou, China.
Zhiliang FanDepartment of Neurology, Xing Tai People's Hospital, Xingtai, China.
Xiaosu YangDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Dongmei HuDepartment of Neurology, The Second Affiliated Hospital of Shandong First Medical University, Jinan, China.
Hongyan XieDepartment of Neurology, The Second Affiliated Hospital of Shandong First Medical University, Jinan, China.
Mingxin LiDepartment of Neurology, Qilu Hospital, Jinan, China.
Bing WenDepartment of Neurology, Qilu Hospital, Jinan, China.
Sufen ChenDepartment of Neurology, Changsha Central Hospital Affiliated to the University of South China, Changsha, China.
Peng XuDepartment of Neurology, Affiliated Hospital of Jining Medical University, Jining, China.
Qingqing RongDepartment of Neurology, Affiliated Hospital of Jining Medical University, Jining, China.
Qiu HeDepartment of Neurology, The People's Hospital of Liaoning Province, Shenyang, China.
Zhanxiu RenDepartment of Neurology, The People's Hospital of Liaoning Province, Shenyang, China.
Fanhong YanDepartment of Neurology, Linyi Jinluo Hospital, Linyi, China.
Heling ZhaoDepartment of Neurology, Linyi Jinluo Hospital, Linyi, China.
Min ChenDepartment of Neurology, Zhengzhou University First Affiliated Hospital, Zhengzhou, China.
Tingmin YuDepartment of Neurology, The Second Hospital of Jilin University, Changchun, China.
Hongli QuDepartment of Neurology, The First Affiliated Hospital of Xiamen University, Xiamen, China.
Xingkai AnDepartment of Neurology, The First Affiliated Hospital of Xiamen University, Xiamen, China.
Huailian GuoDepartment of Neurology, People's Hospital, Peking University, Beijing, China.
Xinhua ZhangDepartment of Neurology, People's Hospital, Peking University, Beijing, China.
Xiaoping PanDepartment of Neurology, Guangzhou First People's Hospital, Guangzhou, China.
Xiaojuan WangDepartment of Neurology, Guangzhou First People's Hospital, Guangzhou, China.
Shi QiuDepartment of Neurology, Aerospace Center Hospital, Beijing, China.
Lvming ZhangDepartment of Neurology, Aerospace Center Hospital, Beijing, China.
Hongling ZhaoDepartment of Neurology, Da Lian Municipal Central Hospital, Dalian, China.
Xin PanDepartment of Neurology, Da Lian Municipal Central Hospital, Dalian, China.
Qi WanDepartment of Neurology, Jiangsu Province Hospital, Nanjing, China.
Lanyun YanDepartment of Neurology, Jiangsu Province Hospital, Nanjing, China.
Jing LiuDepartment of Neurology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Zhe YuDepartment of Neurology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Mingjie ZhangDepartment of Neurology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Ye RanDepartment of Neurology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Xun HanDepartment of Neurology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Zhao DongDepartment of Neurology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Shengyuan YuDepartment of Neurology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Chinese PLA General Hospital · CNFirst Hospital of Jilin University · CNFirst Affiliated Hospital of Soochow University · CNAerospace Center Hospital · CNAffiliated Hospital of Jining Medical University · CNFirst Affiliated Hospital of Xiamen University · CNGuangzhou First People's Hospital · CNJiangsu Province Hospital · CNLiaoning Provincial People's Hospital · CNCentral South University · CNFirst Affiliated Hospital of Zhengzhou University · CNGuangzhou Medical University · CNLishui Central Hospital · CNPeking University · CNPeking University People's Hospital · CNSecond Affiliated Hospital of Jilin University · CNSecond Affiliated Hospital of Zhejiang University · CNSir Run Run Shaw Hospital · CNUniversity of Science and Technology of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMedication-overuse headache (MOH) is a secondary chronic headache disorder that occurs in individuals with a pre-existing primary headache disorder, particularly migraine disorder. Obesity is often combined with chronic daily headaches and is considered a risk factor for the transformation of episodic headaches into chronic headaches. However, the association between obesity and MOH among individuals with migraine has rarely been studied. The present study explored the association between body mass index (BMI) and MOH in people living with migraine.

methodsThis cross-sectional study is a secondary analysis of data from the Survey of Fibromyalgia Comorbidity with Headache study. Migraine and MOH were diagnosed using the criteria of the International Classification of Headache Disorders, 3rd Edition. BMI (kg/m2) is calculated by dividing the weight (kg) by the square of the height (m). Multivariable logistic regression analysis was used to evaluate the association between BMI and MOH.

resultsA total of 2,251 individuals with migraine were included, of whom 8.7% (195/2,251) had a concomitant MOH. Multivariable logistic regression analysis, adjusted for age, sex, education level, headache duration, pain intensity, headache family history, chronic migraine, depression, anxiety, insomnia, and fibromyalgia, demonstrated there was an association between BMI (odds ratio [OR], 1.05; 95% confidence interval [CI], 1.01-1.11; p = 0.031) and MOH. The results remained when the BMI was transformed into a category. Compared to individuals with Q2 (18.5 kg/m2 ≤ BMI ≤23.9 kg/m2), those with Q4 (BMI ≥28 kg/m2) had an adjusted OR for MOH of 1.81 (95% CI, 1.04-3.17; p = 0.037). In the subgroup analyses, BMI was associated with MOH among aged more than 50 years (OR, 1.13; 95%, 1.03-1.24), less than high school (OR, 1.08; 95%, 1.01-1.15), without depression (OR, 1.06; 95%, 1.01-1.12), and without anxiety (OR, 1.06; 95%, 1.01-1.12). An association between BMI and MOH was found in a sensitivity analysis that BMI was classified into four categories according to the World Health Organization guidelines.

conclusionIn this cross-sectional study, BMI was associated with MOH in Chinese individuals with migraine.

Indexed as

Body Mass IndexHeadache Disorders, SecondaryMigraine DisordersObesityAdultComorbidityCross-Sectional StudiesFemaleHumansLogistic ModelsMaleMiddle AgedRisk FactorsBody mass indexCross-sectional studyMedication-overuse headacheMigraine

Identifiers

PMID38569473
PMCPMC11149972
OpenAlexW4393901814

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.