Evidence map›Paper›PMID 38569231›Full record

ReviewCurrent opinion in neurobiology2024

Building and integrating brain-wide maps of nervous system function in invertebrates.

Talya S Kramer, Steven W Flavell

Open access · hybridAbstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. CRASH2p: Closed-loop Two Photon Imaging in a Freely Moving Animal.bioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Talya S KramerPicower Institute for Learning and Memory, Department of Brain & Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA; MIT Biology Graduate Program, Massachusetts Institute of Technology, Cambridge, MA, USA.
Steven W FlavellPicower Institute for Learning and Memory, Department of Brain & Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA. Electronic address: flavell@mit.edu.
Massachusetts Institute of Technology · USMcGovern Institute for Brain Research · US

Funding

Neural Mechanisms that Underlie Flexible Sensory Control of Behavioral States in C. elegansR01DC020484 · NIDCD · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Steven Willem Flavell · 2023 to 2026
$1.5M
Brain-Wide Representations of Behavior During Aversive Internal States in C. ElegansR01NS131457 · NINDS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Steven Willem Flavell · 2023 to 2026
$1.5M
Dissecting the functional organization of the serotonergic system in C. elegansR01GM135413 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI FLAVELL, STEVEN WILLEM · 2020 to 2023
$1.2M
NIDCD NIH HHS R01 DC020484NIGMS NIH HHS R01 GM135413NINDS NIH HHS R01 NS131457
6 · The paper itself

Abstract

The selection and execution of context-appropriate behaviors is controlled by the integrated action of neural circuits throughout the brain. However, how activity is coordinated across brain regions, and how nervous system structure enables these functional interactions, remain open questions. Recent technical advances have made it feasible to build brain-wide maps of nervous system structure and function, such as brain activity maps, connectomes, and cell atlases. Here, we review recent progress in this area, focusing on C. elegans and D. melanogaster, as recent work has produced global maps of these nervous systems. We also describe neural circuit motifs elucidated in studies of specific networks, which highlight the complexities that must be captured to build accurate models of whole-brain function.

Indexed as

BrainCaenorhabditis elegansAnimalsBrain MappingConnectomeDrosophila melanogasterInvertebratesNerve NetNervous System Physiological Phenomena

Identifiers

PMID38569231
PMCPMC11594635
OpenAlexW4393910209

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.