Evidence map›Paper›PMID 38568831›Full record

ArticleJournal of veterinary science2024

Antibiofilm activity of polyethylene glycol-quercetin nanoparticles-loaded gelatin-N,O-carboxymethyl chitosan composite nanogels against

Wanhe Luo, Yongtao Jiang, Jinhuan Liu, Beibei Sun, Xiuge Gao, Samah Attia Algharib, Dawei Guo, Jie Wei, Yurong Wei

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

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  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Wanhe Luo *Engineering Laboratory for Tarim Animal Diseases Diagnosis and Control, College of Animal Science and Technology, Tarim University, Alar 843300, China.ORCID https://orcid.org/0000-0002-5170-1670
Yongtao Jiang *Engineering Laboratory for Tarim Animal Diseases Diagnosis and Control, College of Animal Science and Technology, Tarim University, Alar 843300, China.ORCID https://orcid.org/0000-0002-5146-7693
Jinhuan Liu *Engineering Laboratory for Tarim Animal Diseases Diagnosis and Control, College of Animal Science and Technology, Tarim University, Alar 843300, China.ORCID https://orcid.org/0000-0003-4978-2229
Beibei SunInstrumental Analysis Center, Tarim University, Alar 843300, China.ORCID https://orcid.org/0000-0001-8793-3978
Xiuge GaoEngineering Center of Innovative Veterinary Drugs, Center for Veterinary Drug Research and Evaluation, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.ORCID https://orcid.org/0000-0001-8992-686X
Samah Attia AlgharibDepartment of Clinical Pathology, Faculty of Veterinary Medicine, Benha University, Moshtohor, Toukh 13736, Egypt.ORCID https://orcid.org/0000-0002-3336-2855
Dawei GuoEngineering Center of Innovative Veterinary Drugs, Center for Veterinary Drug Research and Evaluation, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China. gdawei0123@njau.edu.cn.ORCID https://orcid.org/0000-0002-2769-2321
Jie WeiXinjiang Key Laboratory of Animal Infectious Diseases/Institute of Veterinary Medicine, Xinjiang Academy of Animal Sciences, Urumqi 830000, China. xiaojie0717@aliyun.com.ORCID https://orcid.org/0000-0002-1283-4526
Yurong WeiXinjiang Key Laboratory of Animal Infectious Diseases/Institute of Veterinary Medicine, Xinjiang Academy of Animal Sciences, Urumqi 830000, China. weiyu1113@sina.com.ORCID https://orcid.org/0000-0002-7898-6637
Tarim University · CNNanjing Agricultural University · CNXinjiang Academy of Animal Science · CNBenha University · EG

Funding

Innovation and Entrepreneurship Training Program for College Students 202310757001Opening Foundation of Engineering Laboratory for Tarim Animal Diseases Diagnosis and Control of Xinjiang Production & Construction Corps ELDC202303Opening Foundation of Xinjiang Key Laboratory of Animal Infectious Diseases 2023KLA008Program Nanjing Agricultural University-Tarim University Joint Fund NNLH202301Tianshan Talent Training Program: Youth Support Talent Project 2023TSYCQNTJ0033
6 · The paper itself

Abstract

backgroundBiofilms, such as those from

objectivesPolyethylene glycol-quercetin nanoparticles (PQ-NPs)-loaded gelatin-N,O-carboxymethyl chitosan (N,O-CMCS) composite nanogels were prepared and assessed for the on-demand release potential for reducing

methodsThe formation mechanism, physicochemical characterization, and antibiofilm activity of PQ-nanogels against

resultsPhysicochemical characterization confirmed that PQ-nanogels had been prepared by the electrostatic interactions between gelatin and N,O-CMCS with sodium tripolyphosphate. The PQ-nanogels exhibited obvious pH and gelatinase-responsive to achieve on-demand release in the micro-environment (pH 5.5 and gelatinase) of

conclusionsThis study will guide the development of the dual responsiveness (pH and gelatinase) of nanogels to achieve on-demand release for reducing

Indexed as

ChitosanNanoparticlesAnimalsAnti-Bacterial AgentsBiofilmsGelatinGelatinasesNanogelsQuercetinStaphylococcus epidermidisAnti-Bacterial AgentsChitosanGelatinGelatinasesNanogelsO,N-carboxymethylchitosanQuercetinbiofilmnanogelson-demand releasequercetin

Identifiers

PMID38568831
PMCPMC10990912
OpenAlexW4393016320

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.