Evidence map›Paper›PMID 38568479›Full record

ArticleAmerican journal of respiratory and critical care medicine2024

Digital Spatial Profiling Identifies Distinct Molecular Signatures of Vascular Lesions in Pulmonary Arterial Hypertension.

Rubin M Tuder, Aneta Gandjeva, Sarah Williams, Sushil Kumar, Vitaly O Kheyfets, Kyle Matthew Hatton-Jones, Jacqueline R Starr, Jeong Yun, Jason Hong, Nicholas P West and 1 more

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
14.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Ambient PMEnvironment & health (Washington, D.C.) · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. The right time, the right cell: the potential for precision senotherapy in pulmonary arterial hypertension.American journal of physiology. Lung cellular and molecular physiology · 2026
    Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Endothelial Heterogeneity in Pulmonary Hypertension.Arteriosclerosis, thrombosis, and vascular biology · 2026
    Review
  14. Pericytes and Lung Vascular Remodeling.Arteriosclerosis, thrombosis, and vascular biology · 2026
    Review
  15. Review
  16. Article
  17. Article
  18. SETD2 drives METTL14-mediated mCellular and molecular life sciences : CMLS · 2025
    Article
  19. Lung endothelial cell heterogeneity in health and pulmonary vascular disease.American journal of physiology. Lung cellular and molecular physiology · 2025
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Rubin M TuderCardiovascular Pulmonary Research Laboratories, Department of Pediatrics and Department of Medicine.
Aneta GandjevaCardiovascular Pulmonary Research Laboratories, Department of Pediatrics and Department of Medicine.
Sarah WilliamsQueensland Cyber Infrastructure Foundation, St. Lucia, Queensland, Australia.
Sushil KumarCardiovascular Pulmonary Research Laboratories, Department of Pediatrics and Department of Medicine.
Vitaly O KheyfetsProgram in Translational Lung Research, Division of Pulmonary and Critical Care Sciences, Department of Medicine.
Kyle Matthew Hatton-JonesMenzies Health Institute, and.
Jacqueline R StarrChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts; and.
Jeong YunChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts; and.
Jason HongDivision of Pulmonary and Critical Care, Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California.
Nicholas P WestMenzies Health Institute, and.
Kurt R StenmarkCardiovascular Pulmonary Research Laboratories, Department of Pediatrics and Department of Medicine.
Pulmonary Associates · USGriffith University · AUBrigham and Women's Hospital · USUniversity of California, Los Angeles · USUniversity of Colorado Anschutz Medical Campus · US

Funding

Harvard Clinical and Translational Science CenterUM1TR004408 · NCATS · HARVARD MEDICAL SCHOOL · PI Lindsey Robert Baden, Lee Marshall Nadler · 2023 to 2026
$43.3M
VRAC and Rho in pulmonary EC proliferationP01HL014985 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI STENMARK, KURT R. · 1985 to 2019
$35.1M
Role of Complement-Driven Pulmonary Vascular Inflammation in PHP01HL152961 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI DELANEY, CASSIDY A · 2020 to 2024
$14.1M
Bayesian multivariate 3D spatial modeling for microbiome image analysisR01GM126257 · NIGMS · BRIGHAM AND WOMEN'S HOSPITAL · PI LEE, KYU HA, STARR, JACQUELINE R · 2021 to 2024
$2.4M
The role of COPD genetic risk factor HHIP on lymphocytic inflammationK08HL146972 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI YUN, JEONG H · 2020 to 2024
$848k
Integrative Multiomics to Uncover Novel Genes and Networks in Pulmonary Arterial HypertensionK08HL169982 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Jason Hong · 2023 to 2026
$706k
NCATS NIH HHS UM1 TR004408NHLBI NIH HHS K08 HL146972NHLBI NIH HHS K08 HL169982NHLBI NIH HHS P01 HL014985NHLBI NIH HHS P01 HL152961NIGMS NIH HHS R01 GM126257NIH HHS K08HL146972NIH HHS UM1TR004408
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Pulmonary ArteryAdultFamilial Primary Pulmonary HypertensionFemaleGene Expression ProfilingHumansMaleMiddle AgedPulmonary Arterial HypertensionTranscriptomeVascular Remodelingcomplementdigital spatial transcriptomic profilinghypoxiainflammationpulmonary hypertension

Identifiers

PMID38568479
PMCPMC11348978
OpenAlexW4393854186

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.