ReviewNeuroinformatics2024
Gradients of Brain Organization: Smooth Sailing from Methods Development to User Community.
Review in Neuroinformatics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Brain maps of general cognitive functioning: neuroimaging and neurobiological signatures.Translational psychiatry · 2025Pooled it
- Big data and psychiatry: advances, constraints and future directions.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026Article
- Mapping the topographic organization of the human zona incerta using diffusion MRI.bioRxiv : the preprint server for biology · 2026Article
- Individual differences reveal distinct age and pubertal contributions to the refinement of the functional cortical hierarchy during adolescence.bioRxiv : the preprint server for biology · 2026Article
- Article
- Network hierarchy in Alzheimer's and Lewy body spectrum disorders: functional gradients, cognitive phenotypes, and translational gaps.Frontiers in aging neuroscience · 2026Review
- Functional connectivity gradients of the insula in major depressive disorder.Frontiers in psychiatry · 2026Article
- Multiscale Brain Structural Network Reorganization in Diabetic Retinopathy Using Regional Radiomics Similarity Networks.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- Sex Differences in Functional Gradients and Dynamic Functional Connectivity in Preschool-Aged Children With ASD.CNS neuroscience & therapeutics · 2025Article
- Multimodal precision MRI of the individual human brain at ultra-high fields.Scientific data · 2025Article
- Exploring neuroendocrine influences on the sensorimotor-association axis in a female and a male individual.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Brain maps of general cognitive function and spatial correlations with neurobiological cortical profiles.bioRxiv : the preprint server for biology · 2024Article
- Connectome reorganization associated with temporal lobe pathology and its surgical resection.Brain : a journal of neurology · 2024Article
- covSTATIS: a multi-table technique for network neuroscience.Aperture neuro · 2024Article
- Multiscale parcellation of dynamic causal models of the brain.Imaging neuroscience (Cambridge, Mass.)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 13 institutions in 8 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multimodal neuroimaging grants a powerful in vivo window into the structure and function of the human brain. Recent methodological and conceptual advances have enabled investigations of the interplay between large-scale spatial trends - or gradients - in brain structure and function, offering a framework to unify principles of brain organization across multiple scales. Strong community enthusiasm for these techniques has been instrumental in their widespread adoption and implementation to answer key questions in neuroscience. Following a brief review of current literature on this framework, this perspective paper will highlight how pragmatic steps aiming to make gradient methods more accessible to the community propelled these techniques to the forefront of neuroscientific inquiry. More specifically, we will emphasize how interest for gradient methods was catalyzed by data sharing, open-source software development, as well as the organization of dedicated workshops led by a diverse team of early career researchers. To this end, we argue that the growing excitement for brain gradients is the result of coordinated and consistent efforts to build an inclusive community and can serve as a case in point for future innovations and conceptual advances in neuroinformatics. We close this perspective paper by discussing challenges for the continuous refinement of neuroscientific theory, methodological innovation, and real-world translation to maintain our collective progress towards integrated models of brain organization.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.