Evidence map›Paper›PMID 38568466›Full record

ArticleJournal of urban health : bulletin of the New York Academy of Medicine2024

Overdose from Unintentional Fentanyl Use when Intending to Use a Non-opioid Substance: An Analysis of Medically Attended Opioid Overdose Events.

Alexander R Bazazi, Patrick Low, Bryson O Gomez, Hannah Snyder, Jeffrey K Hom, Christine S Soran, Barry Zevin, Michael Mason, Joseph Graterol, Phillip O Coffin

Open access · hybridAbstract read
In one paragraph

Article in Journal of urban health : bulletin of the New York Academy of Medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
13.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 24 citations in OpenAlex.

  1. Estimating the Need for Naloxone Distribution from United States Emergency Departments.Journal of the American College of Emergency Physicians open · 2026
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  7. The Donovan Memorial Lecture: 'Fentanyl-Plus': A New Era of Fentanyl Polydrug Combinations in the North American Overdose Crisis.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Alexander R Bazazi *Division of Substance Abuse and Addiction Medicine at San Francisco General Hospital, Department of Psychiatry and Behavioral Sciences, University of California San Francisco, 1001 Potrero Ave, San Francisco, CA, 94110, USA. alexander.bazazi@ucsf.edu.
Patrick Low *Division of Substance Abuse and Addiction Medicine at San Francisco General Hospital, Department of Psychiatry and Behavioral Sciences, University of California San Francisco, 1001 Potrero Ave, San Francisco, CA, 94110, USA.
Bryson O GomezDivision of Substance Abuse and Addiction Medicine at San Francisco General Hospital, Department of Psychiatry and Behavioral Sciences, University of California San Francisco, 1001 Potrero Ave, San Francisco, CA, 94110, USA.
Hannah SnyderDepartment of Family and Community Medicine, University of California San Francisco, 995 Potrero Ave, San Francisco, CA, 94110, USA.
Jeffrey K HomPopulation Behavioral Health, Behavioral Health Services Division, San Francisco Department of Public Health, 101 Grove St, San Francisco, CA, 94102, USA.
Christine S SoranDivision of Substance Abuse and Addiction Medicine at San Francisco General Hospital, Department of Psychiatry and Behavioral Sciences, University of California San Francisco, 1001 Potrero Ave, San Francisco, CA, 94110, USA.
Barry ZevinStreet Medicine and Shelter Health, San Francisco Department of Public Health, 555 Stevenson St, San Francisco, CA, 94105, USA.
Michael MasonCommunity Paramedicine Division, San Francisco Fire Department, 698 2nd St, San Francisco, CA, 94107, USA.
Joseph GraterolCommunity Paramedicine Division, San Francisco Fire Department, 698 2nd St, San Francisco, CA, 94107, USA.
Phillip O CoffinDivision of HIV, Infectious Diseases and Global Medicine, Department of Medicine, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA, 94143, USA.
San Francisco General Hospital · USNew York City Fire Department · USSan Francisco Department of Public Health · USUniversity of California, San Francisco · USUniversity of San Francisco · US

Funding

Clinical and Translational Science InstituteUL1TR001872 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COLLARD, HAROLD R, JACOBY, VANESSA · 2016 to 2025
$112.1M
Midcareer K24 Award for Mentoring and Patient-Oriented ResearchK24DA042720 · NIDA · SAN FRANCISCO DEPARTMENT OF PUBLIC HEALTH · PI PHILLIP O COFFIN · 2016 to 2026
$1.6M
NCATS NIH HHS UL1 TR001872NIDA NIH HHS K24 DA042720
6 · The paper itself

Abstract

Fentanyl-mixed and substituted heroin is well-documented, but less is known about unintentional fentanyl use among people using stimulants. To determine the prevalence of and racial and ethnic disparities in unintentional fentanyl use among people experiencing a medically attended opioid overdose, we reviewed 448 suspected non-fatal overdose cases attended by a community paramedic overdose response team in San Francisco from June to September 2022. We applied a case definition for opioid overdose to paramedic records and abstracted data on intended substance use prior to overdose. Among events meeting case criteria with data on intended substance use, intentional opioid use was reported by 57.3%, 98.0% of whom intended to use fentanyl. No intentional opioid use was reported by 42.7%, with most intending to use stimulants (72.6%), including methamphetamine and cocaine. No intentional opioid use was reported by 58.5% of Black, 52.4% of Latinx, and 28.8% of White individuals (p = 0.021), and by 57.6% of women and 39.5% of men (p = 0.061). These findings suggest that unintentional fentanyl use among people without opioid tolerance may cause a significant proportion of opioid overdoses in San Francisco. While intentional fentanyl use might be underreported, the magnitude of self-reported unintentional use merits further investigation to confirm this phenomenon, explore mechanisms of use and disparities by race and ethnicity, and deploy targeted overdose prevention interventions.

Indexed as

FentanylAdultAnalgesics, OpioidDrug OverdoseFemaleHumansMaleMiddle AgedOpiate OverdoseOpioid-Related DisordersPrevalenceSan FranciscoYoung AdultAnalgesics, OpioidFentanylEmergency medical servicesFentanylOpioidOverdoseStimulant

Identifiers

PMID38568466
PMCPMC11052958
OpenAlexW4393899373

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.