Evidence map›Paper›PMID 38568361›Full record

ArticleActa parasitologica2024

Synergistic Interaction Effect of Artemisia cina n-hexane Extract and Tagetes lucida Ethyl Acetate Extract on Haemonchus Contortus.

Itzel Santiago-Figueroa, Manases González-Cortazar, Julieta Gertrudis Estrada-Flores, Jorge Alfredo Cuéllar-Ordaz, María Eugenia López-Arellano, Francisco Javier González-Reyes, Agustín Olmedo-Juárez, Rosa Isabel Higuera-Piedrahita

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta parasitologica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Using an Aqueous Suspension ofPathogens (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Itzel Santiago-FigueroaFacultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de México, Carr. Cuautitlán- Teoloyucan Km 2.5, Col. San Sebastián Xhala, CP 54714, Cuautitlán, México.ORCID http://orcid.org/0000-0003-2535-2398
Manases González-CortazarCentro de Investigación Biomédica Del Sur, Instituto Mexicano del Seguro Social (IMSS), Argentina No. 1, 62790, Xochitepec, CP, México.ORCID http://orcid.org/0000-0002-3693-1670
Julieta Gertrudis Estrada-FloresInstituto de Ciencias Agropecuarias y Rurales (ICAR), Universidad Autónoma del Estado de México (UAEM), Estado de México, Campus UAEM El Cerrillo, El Cerrillo Piedras Blancas, 50090, Toluca, México.ORCID http://orcid.org/0000-0002-3376-5128
Jorge Alfredo Cuéllar-OrdazFacultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de México, Carr. Cuautitlán- Teoloyucan Km 2.5, Col. San Sebastián Xhala, CP 54714, Cuautitlán, México.ORCID http://orcid.org/0000-0002-9231-1556
María Eugenia López-ArellanoCentro de Investigación Disciplinaria en Salud Animal e Inocuidad, Agrícolas y Pecuarias (INIFAP), Instituto Nacional de Investigaciones Forestales, Carr. Fed. Cuernavaca-Cuautla No. 8534, CP 62550, Jiutepec, México.ORCID http://orcid.org/0000-0001-5499-7449
Francisco Javier González-ReyesUniversidad Autónoma Chapingo, Carr. México-Texcoco Km 38.5, C.P. 56230, Chapingo, Estado de México, México.ORCID http://orcid.org/0000-0002-1429-0331
Agustín Olmedo-JuárezCentro de Investigación Disciplinaria en Salud Animal e Inocuidad, Agrícolas y Pecuarias (INIFAP), Instituto Nacional de Investigaciones Forestales, Carr. Fed. Cuernavaca-Cuautla No. 8534, CP 62550, Jiutepec, México. aolmedoj@gmail.com.ORCID http://orcid.org/0000-0001-9872-9112
Rosa Isabel Higuera-PiedrahitaFacultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de México, Carr. Cuautitlán- Teoloyucan Km 2.5, Col. San Sebastián Xhala, CP 54714, Cuautitlán, México. rhiguera05@comunidad.unam.mx.ORCID http://orcid.org/0000-0003-4657-0159

Funding

NESA Acupuncture Research CollaborativeU19AT002022 · NCCIH · NEW ENGLAND SCHOOL OF ACUPUNCTURE · PI WAYNE, PETER MICHAEL · 2003 to 2009
$4.0M
NCCIH NIH HHS U19 AT002022PAPIIT IA204822
6 · The paper itself

Abstract

purposeWe analysed the possible synergistic activity among active extracts from Artemisia cina and Tagetes lucida combinations on Haemonchus contortus, a nematode parasitising sheep.

methodsThe work was carried out in vitro on eggs and infective larvae (L3) of H. contortus. The results were analysed with SAS 9.1, applying the ANOVA and Tukey test, and the lethal concentration (LC) values LC50 and LC90 were determined with regression analysis, employing Proc Probit of SAS 9.1. Additionally, the lethal concentration (LC) was calculated with LC

resultsThe results demonstrated a high efficacy of the two plants studied on both nematode eggs and L3 larvae as well as of their combinations. The highest egg hatching inhibition was obtained with a 50/50 combination, and the best larvae mortality was obtained with 25% A. cina and 75% T. lucida at 10 mg/mL. Additionally, this combination showed a synergistic effect.

conclusionThe two plant species studied here can be applied as natural anthelmintic alternatives due to their high bioactive effect and synergistic response.

Indexed as

AnthelminticsArtemisiaDrug SynergismHaemonchusLarvaPlant ExtractsTagetesAcetatesAnimalsHaemonchiasisHexanesOvumSheepSheep DiseasesAcetatesAnthelminticsethyl acetateHexanesn-hexanePlant ExtractsBioactive PlantsGastroenteric NematodesPharmacology InteractionSmall RuminantsSustainable Anthelmintic

Identifiers

PMID38568361
PMCPMC11182837

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.