Evidence map›Paper›PMID 38568326›Full record

ReviewCurrent rheumatology reports2024

AA Amyloidosis: A Contemporary View.

Safak Mirioglu, Omer Uludag, Ozge Hurdogan, Gizem Kumru, Ilay Berke, Stavros A Doumas, Eleni Frangou, Ahmet Gul

Open access · hybridAbstract readReview
In one paragraph

Review in Current rheumatology reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Unraveling cardiac amyloidosis in Egypt: diagnostic challenges and disease outcomes.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. [An unusual cause for kidney transplantation].Innere Medizin (Heidelberg, Germany) · 2026
    Article
  7. Article
  8. Pathogenesis and kidney prognosis of renal amyloidosis.Cellular and molecular life sciences : CMLS · 2026
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Diffuse uptake in the subcutaneous tissue onEuropean journal of nuclear medicine and molecular imaging · 2026
    Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Safak MiriogluDivision of Nephrology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey. smirioglu@gmail.com.
Omer UludagDivision of Rheumatology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Ozge HurdoganDepartment of Pathology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Gizem KumruDivision of Nephrology, Ankara University Faculty of Medicine, Ankara, Turkey.
Ilay BerkeDivision of Nephrology, Marmara University School of Medicine, Istanbul, Turkey.
Stavros A DoumasDepartment of Medicine, MedStar Georgetown University Hospital, Washington, DC, USA.
Eleni FrangouDepartment of Nephrology, Limassol General Hospital, State Health Services Organization, Limassol, Cyprus.
Ahmet GulDivision of Rheumatology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Istanbul University · TRAnkara University · TRLimassol General Hospital · CYMarmara University · TRMedStar Georgetown University Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewAmyloid A (AA) amyloidosis is an organ- or life-threatening complication of chronic inflammatory disorders. Here, we review the epidemiology, causes, pathogenesis, clinical features, and diagnostic and therapeutic strategies of AA amyloidosis. RECENT

findingsThe incidence of AA amyloidosis has declined due to better treatment of the underlying diseases. Histopathological examination is the gold standard of diagnosis, but magnetic resonance imaging can be used to detect cardiac involvement. There is yet no treatment option for the clearance of amyloid fibril deposits; therefore, the management strategy primarily aims to reduce serum amyloid A protein. Anti-inflammatory biologic agents have drastically expanded our therapeutic armamentarium. Kidney transplantation is preferred in patients with kidney failure, and the recurrence of amyloidosis in the allograft has become rare as transplant recipients have started to benefit from the new agents. The management of AA amyloidosis has been considerably changed over the recent years due to the novel therapeutic options aiming to control inflammatory activity. New agents capable of clearing amyloid deposits from the tissues are still needed.

Indexed as

AmyloidosisHumansKidney TransplantationSerum Amyloid A ProteinSerum Amyloid A ProteinAmyloidosisArthritisAutoinflammatory diseasesChronic infectionChronic inflammationSerum amyloid A

Identifiers

PMID38568326
PMCPMC11219434
OpenAlexW4393901851

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.