Evidence map›Paper›PMID 38568216›Full record

ReviewOrthopadie (Heidelberg, Germany)2024

Evidence for cemented TKA and THA based on a comparison of international register data.

Martina Humez, Katharina Kötter, Ralf Skripitz, Klaus-Dieter Kühn

Erratum issuedOpen access · hybridAbstract readComparative StudyReview
In one paragraph

Review in Orthopadie (Heidelberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Martina HumezInstitute of Hygiene and Environmental Medicine, Justus-Liebig-Universität Giessen, Schubertstraße 81, 35392, Giessen, Germany. martina.humez@mikrobio.med.uni-giessen.de.
Katharina KötterHeraeus Medical GmbH, Wehrheim, Germany.
Ralf SkripitzCentre for Endoprosthetics, Foot Surgery, Paediatric and General Orthopaedics, Roland-Klinik Bremen, Bremen, Germany.
Klaus-Dieter KühnDepartment of Orthopaedics and Orthopaedic Surgery, Medical University of Graz, Graz, Germany.
Heraeus (Germany) · DEJustus-Liebig-Universität Gießen · DERoland Mills United (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHip and knee implants can either be fixed without cement, press-fit, or with bone cement. Real-world data from arthroplasty registers, as well as studies provide a broad database for the discussion of cemented versus uncemented arthroplasty procedures.

objectiveWhat does current evidence from international arthroplasty registries and meta-analyses recommend regarding cemented or cementless fixation of hip and knee implants?

methodsA recommendation is generated by means of direct data comparison from the arthroplasty registries of eight countries (USA, Germany, Australia, UK, Sweden, Norway, New Zealand, Netherlands), the comparison of 22 review studies and meta-analyses based on registry data, as well as an evaluation of recommendations of healthcare systems from different nations. For this purpose, reviews and meta-analyses were selected where the results were statistically significant, as were the annual reports of the arthroplasty registries that were current at the time of writing.

resultsFor knee arthroplasties, long survival time as well as lower risk of revision can be achieved with the support of cemented fixation with antibiotic-loaded bone cement. In patients aged 70 years and older, cemented fixation of hip stem implants significantly reduces risk of intraoperative or postoperative periprosthetic fracture (quadruple). This applies both to elective total hip arthroplasties and to hemiarthroplasty after femoral neck fractures. Antibiotic-loaded bone cement significantly (p = 0.041) reduces the risk of periprosthetic infection, especially in patients with femoral neck fractures.

conclusionTotal knee replacement with antibiotic-loaded bone cement is well established internationally and is evidence-based. Registry data and meta-analyses recommend cemented fixation of the hip stem in older patients. In Germany, USA and Australia these evidence-based recommendations still must be transferred to daily practice.

Indexed as

Arthroplasty, Replacement, HipArthroplasty, Replacement, KneeBone CementsRegistriesAgedCementationEvidence-Based MedicineFemaleHip ProsthesisHumansInternationalityMaleMeta-Analysis as TopicReview Literature as TopicTreatment OutcomeBone CementsArthroplasty registerBone cementImplant fixationPeriprosthetic fractureRevision risk

Identifiers

PMID38568216
PMCPMC11329679
OpenAlexW4393893195

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.