Evidence map›Paper›PMID 38567968›Full record

ArticleEnvironmental health perspectives2024

Association between Fine Particulate Matter Exposure and Cerebrospinal Fluid Biomarkers of Alzheimer's Disease among a Cognitively Healthy Population-Based Cohort.

Emma Casey, Zhenjiang Li, Donghai Liang, Stefanie Ebelt, Allan I Levey, James J Lah, Thomas S Wingo, Anke Hüls

Open access · diamondAbstract read
In one paragraph

Article in Environmental health perspectives, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Factors associated with age at tau pathology onset and time from tau onset to dementia in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  10. Review
  11. Article
  12. Association between chronic PMBMC public health · 2025
    Article
  13. Review
  14. Review
  15. Article
  16. Rural Roads to Cognitive Resilience (RRR): A prospective cohort study protocol.medRxiv : the preprint server for health sciences · 2024
    Article
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Emma CaseyDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.ORCID 0009-0006-4303-4755
Zhenjiang LiGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Donghai LiangDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Stefanie EbeltDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Allan I LeveyDepartment of Neurology, School of Medicine, Emory University, Atlanta, Georgia, USA.
James J LahDepartment of Neurology, School of Medicine, Emory University, Atlanta, Georgia, USA.
Thomas S WingoDepartment of Neurology, School of Medicine, Emory University, Atlanta, Georgia, USA.
Anke HülsDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.ORCID 0000-0002-6005-417X
Emory University · US

Funding

The Emory Healthy Brain Study: Discovering Predictive Biomarkers for Alzheimer's DiseaseR01AG070937 · NIA · EMORY UNIVERSITY · PI LAH, JAMES J · 2021 to 2025
$35.2M
The Emory Alzheimer's Disease CenterP50AG025688 · NIA · EMORY UNIVERSITY · PI WINGO, THOMAS SPURGEON · 2005 to 2019
$25.7M
UC Davis Alzheimer's Disease Research CenterP30AG072972 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Charles DeCarli, Rachel A Whitmer · 2021 to 2026
$25.2M
Pilot Project ProgramP30ES019776 · NIEHS · EMORY UNIVERSITY · PI William Michael Caudle · 2013 to 2026
$22.6M
The brain multi-omic approach to identify key molecular drivers of neuropsychiatric symptoms in Alzheimer's dementiaR01AG072120 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Aliza Pham Wingo, Thomas Spurgeon Wingo · 2022 to 2026
$4.3M
Integrative genomic, transcriptomic, and proteomic analyses to investigate sex-specific differences in Alzheimer's DiseaseR01AG075827 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Aliza Pham Wingo, Thomas Spurgeon Wingo · 2022 to 2026
$3.7M
Air pollution and early signs of dementiaR01AG079170 · NIA · EMORY UNIVERSITY · PI Anke Huels, Thomas Spurgeon Wingo · 2022 to 2026
$3.6M
Air pollution, the blood and brain metabolome and their effects on Alzheimer's disease and related dementiasR01AG087250 · NIA · EMORY UNIVERSITY · PI Anke Huels, Donghai Liang · 2024 to 2026
$2.3M
Traffic Exposure, Maternal Metabolome and Birth Outcomes Study (TEMMBO Study)R21ES032117 · NIEHS · EMORY UNIVERSITY · PI LIANG, DONGHAI · 2021 to 2022
$420k
NIA NIH HHS P30 AG072972NIA NIH HHS P50 AG025688NIA NIH HHS R01 AG070937NIA NIH HHS R01 AG072120NIA NIH HHS R01 AG075827NIA NIH HHS R01 AG079170NIA NIH HHS R01 AG087250NIEHS NIH HHS P30 ES019776NIEHS NIH HHS R21 ES032117
6 · The paper itself

Abstract

backgroundEpidemiological evidence suggests air pollution adversely affects cognition and increases the risk of Alzheimer's disease (AD), but little is known about the biological effects of fine particulate matter (

objectivesWe investigated the association between 1-, 3-, and 5-y exposure to ambient and traffic-related

methodsWe conducted a cross-sectional analysis using data from 1,113 cognitively healthy adults (45-75 y of age) from the Emory Healthy Brain Study in Georgia in the United States. CSF biomarker concentrations of

resultsInterquartile range (IQR;

conclusionIn our study, consistent trends were found between 1-y

Indexed as

Air PollutantsAir PollutionAlzheimer DiseaseAdultBiomarkersCross-Sectional StudiesEnvironmental ExposureHumansParticulate MatterUnited StatesAir PollutantsBiomarkersParticulate Matter

Identifiers

PMID38567968
PMCPMC10989269
OpenAlexW4393871416

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.