Evidence map›Paper›PMID 38567686›Full record

ArticleThe journals of gerontology. Series B, Psychological sciences and social sciences2024

Social Activities and Risk of Dementia in Community-Dwelling Older People: Gender-Specific Findings From a Prospective Cohort Study.

Htet Lin Htun, Achamyeleh Birhanu Teshale, Alice J Owen, Joanne Ryan, Robyn L Woods, Suzanne G Orchard, André Hajek, Thom Lysen, Raj C Shah, Trevor T-J Chong and 4 more

Open access · hybridAbstract read
In one paragraph

Article in The journals of gerontology. Series B, Psychological sciences and social sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Childcare engagement among older adults in Australia and subsequent physical, psychosocial, and behavioral health outcomes.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2025
    Article
  6. Gender-specific analysis of social connection patterns and risk of dementia in community-dwelling older people.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 3 countries.

Htet Lin HtunSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0003-2307-0610
Achamyeleh Birhanu TeshaleSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0002-7572-9993
Alice J OwenSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0002-4807-6069
Joanne RyanSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0002-7039-6325
Robyn L WoodsSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0003-1249-6149
Suzanne G OrchardSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0003-0211-3183
André HajekDepartment of Health Economics and Health Services Research, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID 0000-0002-6886-2745
Thom LysenIndependent Researcher, Utrecht, The Netherlands.ORCID 0000-0002-7593-935X
Raj C ShahDepartment of Family and Preventive Medicine and the Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.ORCID 0000-0001-9706-9730
Trevor T-J ChongTurner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0001-7764-3811
Kerry M SheetsDepartment of Medicine, University of Minnesota, Minneapolis, Minnesota, USA.ORCID 0000-0002-3492-2404
Johanna JoyceFaculty of Medicine, University of Queensland, Brisbane, Queensland, Australia.ORCID 0000-0001-7593-2564
Anne M MurrayDivision of Geriatric Medicine, Department of Medicine, Hennepin Healthcare, Minneapolis, Minnesota, USA.ORCID 0000-0002-2787-8433
Rosanne Freak-PoliSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0003-4072-8699
Monash University · AUBerman Center for Outcomes and Clinical Research · USMonash Health · AURush University Medical Center · USThe University of Queensland · AUUniversität Hamburg · DEUniversity of Minnesota · US

Funding

ASPirin in Reducing Events in the ElderlyU01AG029824 · NIA · HENNEPIN HEALTHCARE RESEARCH INSTITUTE · PI MCNEIL, JOHN JAMES, MURRAY, ANNE M · 2009 to 2018
$64.6M
Main Administrative CoreU19AG062682 · NIA · HENNEPIN HEALTHCARE RESEARCH INSTITUTE · PI CHAN, ANDREW T, MCNEIL, JOHN JAMES · 2019 to 2023
$42.9M
NCI NIH HHS U01AG029824NIA NIH HHS U19 AG062682
6 · The paper itself

Abstract

objectivesThis study examines the gender-specific associations between a wide range of social activities and dementia risk.

methodsA prospective cohort study was conducted involving community-dwelling older Australians (≥70 years) without significant cognitive impairment at enrolment. During the first year of enrolment, we assessed 25 self-reported social activities covering various aspects, including support from relatives and friends, community participation, social interactions with surroundings, and loneliness. Dementia diagnosis followed DSM-IV criteria, adjudicated by an international expert panel. To estimate hazard ratios (HR) and 95% confidence intervals (CI) for associations between social activities and dementia, we performed Cox proportional hazards models, adjusting for age, educational attainment, baseline global cognition, and depressive symptoms.

resultsAmong 9,936 participants who completed all social activity questionnaires (median [IQR] age: 73.4 [71.6-77.1] years; 47.4% men), dementia was diagnosed in 3.8% of men (n = 181/4,705) and 2.6% of women (n = 138/5,231) over a median 6.4 years (IQR: 5.3-7.6, range: 0.2-10.1) follow-up. Gender-specific relationships emerged: caregiving for a person with illness/disability in women (HR: 0.65, 95% CI: 0.42-0.99), and having ≥9 relatives feeling close to call for help in men (HR: 0.56, 95% CI: 0.33-0.96; reference <9 relatives) were associated with reduced dementia risk. Unexpectedly, in women, having ≥5 friends with whom they felt comfortable discussing private matters were associated with a greater dementia risk (HR: 1.69, 95% CI: 1.10-2.59; reference ≤2 friends). Imputed models further identified that babysitting/childminding was associated with lower dementia risk in men (HR: 0.75, 95% CI: 0.56-0.99). No other social activities showed significant associations with dementia. DISCUSSION: This study provides evidence of social activities influencing dementia risk. Further investigations are required to uncover the mechanisms driving these observed relationships.

Indexed as

DementiaSocial ParticipationAgedAustralasian PeopleAustraliaFemaleHumansIndependent LivingMaleProspective StudiesRisk FactorsCohort studiesSocial determinants of healthSocial isolationSocial participationSocial support

Identifiers

PMID38567686
PMCPMC11025553
OpenAlexW4393952540

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.