Evidence map›Paper›PMID 38567541›Full record

ArticleHuman vaccines & immunotherapeutics2024

HPV-specific antibodies in female genital tract secretions captured via first-void urine retain their neutralizing capacity.

Laura Téblick, Marijana Lipovac, Freya Molenberghs, Peter Delputte, Winnok H De Vos, Alex Vorsters

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07303751 (HPV Vaccination and Infectivity Reduction in HPV-positive Women), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07303751 phase2not yet recruitingnot on this mapstarted 2026, after this paper: background citation

HPV Vaccination and Infectivity Reduction in HPV-positive Women

TypeinterventionalSponsorInstitut d'Investigació Biomèdica de BellvitgeRan2026 to 2027Enrolled80ConditionsHPV, High-risk HPV (Any Strain), Human Papillomavirus (HPV) InfectionsArmsNonavalent HPV vaccine (9vHPV)
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. UnveilingiScience · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Laura TéblickCentre for the Evaluation of Vaccination, Vaccine & Infectious Disease Institute, University of Antwerp, Antwerp, Belgium.ORCID 0000-0002-7484-0956
Marijana LipovacCentre for the Evaluation of Vaccination, Vaccine & Infectious Disease Institute, University of Antwerp, Antwerp, Belgium.
Freya MolenberghsLaboratory of Cell Biology and Histology, University of Antwerp, Antwerp, Belgium.
Peter DelputteLaboratory for Microbiology, Parasitology and Hygiene, University of Antwerp, Antwerp, Belgium.
Winnok H De VosLaboratory of Cell Biology and Histology, University of Antwerp, Antwerp, Belgium.
Alex VorstersCentre for the Evaluation of Vaccination, Vaccine & Infectious Disease Institute, University of Antwerp, Antwerp, Belgium.
University of Antwerp · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human papillomavirus (HPV) vaccines, primarily relying on neutralizing antibodies, have proven highly effective. Recently, HPV-specific antibodies have been detected in the female genital tract secretions captured by first-void urine (FVU), offering a minimally invasive diagnostic approach. In this study, we investigated whether HPV16-specific antibodies present in FVU samples retain their neutralizing capacity by using pseudovirion-based neutralization assays. Paired FVU and serum samples (vaccinated

Indexed as

Papillomavirus InfectionsPapillomavirus VaccinesAdolescentAdultAntibodies, NeutralizingAntibodies, ViralFemaleGenitalia, FemaleHuman papillomavirus 16HumansImmunoglobulin GNeutralization TestsReproducibility of ResultsYoung AdultAntibodies, NeutralizingAntibodies, ViralImmunoglobulin GPapillomavirus Vaccinesfirst-void urineHPVhuman papillomavirusNeutralizationvaccination

Identifiers

PMID38567541
PMCPMC10993920
OpenAlexW4393857576

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.